Results 71 to 80 of about 221,955 (289)
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
A Common Language of Software Evolution in Repositories (CLOSER)
SoftwareVersion Control Systems (VCSs) are used by development teams to manage the collaborative evolution of source code, and there are several widely used industry standard VCSs.
Jordan Garrity, David Cutting
doaj +1 more source
eXframe: reusable framework for storage, analysis and visualization of genomics experiments
BMC Bioinformatics, 2011 Background Genome-wide experiments are routinely conducted to measure gene expression, DNA-protein interactions and epigenetic status. Structured metadata for these experiments is imperative for a complete understanding of experimental conditions, to ...
Sinha Amit U +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Applied Sciences, 2019 The plethora of open source clinical software offers great reuse opportunities for developers to build clinical tools at lower cost and at a faster pace.
Zhengru Shen, Marco Spruit
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
A Different Shade of Green: A Survey of Indonesian Higher Education Institutional Repositories
Journal of Librarianship and Scholarly Communication, 2017 INTRODUCTION Institutional repositories (IRs) are an accepted part of the open access landscape, and they have a particular role to play in supporting scholarly communication in developing countries, such as Indonesia.
Paul Genoni, Toong Tjiek Liauw
doaj +2 more sources
A Quantitative Study of Java Software Buildability
, 2017 Researchers, students and practitioners often encounter a situation when the build process of a third-party software system fails. In this paper, we aim to confirm this observation present mainly as anecdotal evidence so far.
Beller M. +4 more
core +1 more source