Results 131 to 140 of about 174,852,288 (260)

Cutting Force Mechanisms in Drilling 90MnCrV8 Tool Steel: ANOVA and Theoretical Insights

Journal of Manufacturing and Materials Processing
This study investigates the influence of tool geometry and cutting parameters on thrust forces and process stability during the drilling of 90MnCrV8, a hard and wear-resistant tool steel. The objective was to identify the dominant and interactive effects
Jaroslava Fulemová, Josef Sklenička, Jan Hnátík, Miroslav Gombár, Jindřich Sýkora, Michal Povolný, Adam Lukáš   +6 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Results of analysis of variance (ANOVA) of fertilization treatments according to environments for investigated beetroot properties.

, 2019
Results of analysis of variance (ANOVA) of fertilization treatments according to environments for investigated beetroot properties.
Tomislav Karažija (7353668), Marija Pecina (7353665), Szilvia Veres (6812894), Mirjana Herak Ćustić (7353677), Boris Lazarević (7353671), Marko Petek (110914), Nina Toth (7353662), Igor Palčić (7353674)   +7 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Analysis of variance (ANOVA) testing the effect of clone, year, and clone × year interaction of AUDPC.

, 2013
Analysis of variance (ANOVA) testing the effect of clone, year, and clone × year interaction of AUDPC.
Carl J. Douglas (483841), Robert D. Guy (483840), Yousry A. El-Kassaby (203286), Shawn D. Mansfield (483842), Shofiul Azam (483839), Jonathan La Mantia (483838), Jaroslav Klápště (203291), Richard Hamelin (86535)   +7 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Analysis of variance (ANOVA) for the contents of active ingredients and seven primary ecological factors.

, 2015
Analysis of variance (ANOVA) for the contents of active ingredients and seven primary ecological factors.
Xiaowen Zhao (540788), Dongxue Yin (645149), Jianjun Liu (28194), Wei Liu (20030)   +3 more
core   +1 more source

Spatio-temporal variation and relationship between agricultural efficiency and irrigation intensity in a semi-arid region of India

Regional Sustainability
A surging population in Karnataka State, a semi-arid region in India, poses a threat to both food security and livelihood sustainability, necessitating a concentrated effort to bolster agricultural efficiency and achieve United Naton’s Sustainable ...
Shibu Das, Kaushal Kumar Sharma, Suranjan Majumder, Debabrata Das, Indrajit Roy Chowdhury   +4 more
doaj   +1 more source