Results 181 to 190 of about 785,321 (238)

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

Advanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang, Daniel P. Mayer, Prabhat K. Purbey, Yingzi Liu, Kindra Kelly‐Scumpia, Clara Kang, Natalie Tsubamoto, Dhriti Bolangadi, Iqra Arshad, Charisse Ng, Maksim V. Plikus, Dino Di Carlo, Jason S. Weinstein, Philip O. Scumpia   +13 more
wiley   +1 more source

An empirical study on exercise addiction and grit among college students: based on 35 exercise sessions. [PDF]

Front Psychol
Jiang J, Huang Y, Sang Y, Zhou X, Hou S, Li L.   +5 more
europepmc   +1 more source

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

Advanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia, Constantine Vogiatzis, Alejandra Planells‐Devesa, Emre Dikici, Caroline Vieira Maluf, Vasudev Vivekanand Nayak, Paulo G. Coelho, Lukasz Witek, Alicia Bilbao, Daniel Bilbao, Prasoon Mohan, Sapna Deo, Sylvia Daunert   +12 more
wiley   +1 more source

Analyzing Trends in the Incidence of Trauma and Mechanisms of Injury Before, During, and After COVID-19 Lockdown in a Staten Island Level 1 Trauma Center. [PDF]

Cureus
Bogdanovski DA, Rubinshteyn V, Harrington T, LeBaron J, Cohen D, Issack PS, Basu A.   +6 more
europepmc   +1 more source

Mechanically Mutable Matrices: A Hierarchical Investigation of Decellularized Sea Cucumber Collagen as an Adaptable Scaffold Material

Advanced Functional Materials, EarlyView.
Sea cucumber mutable collagenous tissue (MCT) is a remarkable collagen‐based material which can rapidly undergo large changes in stiffness through transiently bound effector proteins. Here, we investigate the hierarchical structure and mechanical response of MCT from Cucumaria frondosa across length scales with a wide range of methods, also exploring ...
Nathalie R. H. Singh, Amy K. Lin, Sabra Rostami, Cameron Hastie, Paul W. Wiseman, Patrick Flammang, Christopher Moraes, Matthew J. Harrington   +7 more
wiley   +1 more source

Morpho-Reproductive Stability of Rice Landraces Under Water Deficit Across Agroecological Zones of Far-West Nepal. [PDF]

Plant Environ Interact
Lamichhane N, Dhami U, Bhandari S, Pant G, Thapa LB, Pokhrel CP, Yadav RKP.   +6 more
europepmc   +1 more source

Tough and Skin‐Free Porous Polyelectrolyte Complex Hydrogels via Salt‐Induced Aqueous Phase Separation

Advanced Functional Materials, EarlyView.
Controlling counterion exchange rate during aqueous phase separation enables the formation of skin‐free, homogeneously porous polyelectrolyte complex hydrogels by suppressing kinetically trapped skin layers and macrovoids. The resulting hydrogel networks exhibit exceptional toughness (∼15 MJ·m−3) and enable 3D (bio)printing and post‐functionalization ...
Adrivit Mukherjee, Vishakha Vishakha, Julien Es Sayed, Hugo Brummer, Peter Dijkstra, Ajay Giri Prakash Kottapalli, Ranjita K. Bose, Marleen Kamperman   +7 more
wiley   +1 more source

CRISPLD2 protects against liver inflammation and fibrosis via GRP78 to repress HMGB1/TLR4 axis-mediated STING palmitoylation. [PDF]

Hepatol Commun
Zhang H, Wang J, Yang H, Yan Y, Zou J, Liu Z.   +5 more
europepmc   +1 more source

Hypoxia-induced Schwann cells-derived extracellular vesicles carrying LncRNA TNXA-PS1 promote recovery post sciatic nerve injury. [PDF]

Commun Biol
Hao Z, Wang Z, Jia J, Wang Y, Wu T, Fan Y, Huo Z, Zhao X, Yan S, Wang B, Qicheng A.   +10 more
europepmc   +1 more source

Replacing fish oil with Tetraselmis chui microalgae biomass does not compromise rainbow trout health: Biochemical, histologic, antioxidant and immune gene expression. [PDF]

Sci Rep
Iheanacho S, Simon A, Mueller J, Lippemer S, Rebl A, Hasler M, Schulz C.   +6 more
europepmc   +1 more source