Results 241 to 250 of about 2,009,025 (329)

MetaboMiNR: An Online Tool to Analyze Label-Free Proteomic Experiments With a Focus on Metabolism and Nuclear Receptors.

Endocrinology
Saikali MF, Cummins CL.
europepmc   +1 more source

Dietary Patterns Among Patients With Beta-Thalassemia Major in Vietnam. [PDF]

J Hum Nutr Diet
Hoang TNA, Quach HL.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Framework of processing Analysis Ready Data (initial design)

Initial design of a framework of Analysis Ready Data processing.
openaire   +1 more source

Can viable bacteria be present in the surface of ready-to-use surgical instruments? [PDF]

Rev Col Bras Cir
Sauer CRO, Aoki FH, Kuboyama RH, Lima MRS, Saraiva IHBL, Silva CB, Fernandes Neto FA, Salles MJDC.   +7 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Letter to editor: Intradiscal steroid injection for lumbar canal stenosis: novel but not yet ready for clinical adoption. [PDF]

Asian Spine J
Khurana G, Singla V, Ghai B.
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Availability and readiness of health facilities for non-communicable disease services in Ethiopia: Evidence from the nationally representative health facility survey 2022. [PDF]

PLoS One
Aschalew AY, Kelkay JM, Teshale G, Demissie KA, Baykemagn ND, Tadele A, Tiruneh MG, Tafere TZ, Hagos A, Jejaw M.   +9 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source