Results 41 to 50 of about 1,828,537 (231)

Level sets estimation and Vorob'ev expectation of random compact sets

, 2011
The issue of a "mean shape" of a random set $X$ often arises, in particular in image analysis and pattern detection. There is no canonical definition but one possible approach is the so-called Vorob'ev expectation $\E_V(X)$, which is closely linked to ...
Baddeley, Baddeley, Colless, Cuevas, Cuevas, Davydov, Falconer, Garban, Kovyazin, Lantuéjoul, Lawler, Lawler, Ledoux, Li, Martinez, Mason, Molchanov, Molchanov, Molchanov, Molchanov, Molchanov, Molchanov, Møller, Randon-Furling, Rigollet, Roques, Schneider, Singh, Stoica, Stoica, Stoica, Stoica, Stoyan, Stoyan, Stoyan, Tsybakov, van Lieshout, van Lieshout, van Lieshout   +38 more
core   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Kesiapan Pedagogik Mahasiswa Bkk Akuntansi Uns Dalam Melaksanakan Program Pengalaman Lapangan Tahun 2013 [PDF]

, 2014
The objective of this research is to investigate readiness of students in implementing Field Experience Program viewed from pedagogical competency of students of the Special Expertise Field of Accounting.This research used the descriptive qualitative ...
Retnowati, A. (Agustin), Siswandari, S. (Siswandari), Sukirman, S. (Sukirman)   +2 more
core  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

A Mock Data and Science Challenge for Detecting an Astrophysical Stochastic Gravitational-Wave Background with Advanced LIGO and Advanced Virgo

, 2015
The purpose of this mock data and science challenge is to prepare the data analysis and science interpretation for the second generation of gravitational-wave experiments Advanced LIGO-Virgo in the search for a stochastic gravitational-wave background ...
Christensen, Nelson, Coughlin, Michael, Kandhasamy, Shivaraj, Mandic, Vuk, Meacher, Duncan, Morris, Sean, Regimbau, Tania, Romano, Joseph D., Thrane, Eric   +8 more
core   +4 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data [PDF]

Bioinformatics, 2016
Abstract Summary Open access to raw clinical and molecular data related to immunological studies has created a tremendous opportunity for data-driven science. We have developed RImmPort that prepares NIAID-funded research study datasets in ImmPort (immport.org) for analysis in R. RImmPort comprises of
Shankar, Ravi D, Bhattacharya, Sanchita, Jujjavarapu, Chethan, Andorf, Sandra, Wiser, Jeffery A, Butte, Atul J   +5 more
openaire   +4 more sources

Modeling Semantic Plausibility by Injecting World Knowledge

, 2018
Distributional data tells us that a man can swallow candy, but not that a man can swallow a paintball, since this is never attested. However both are physically plausible events.
Durrett, Greg, Erk, Katrin, Wang, Su
core   +1 more source