Results 51 to 60 of about 1,828,537 (231)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

EFFECTIVENESS OF ALTERNATIVE EXPORT PROMOTION STRATEGIES FOR BRANDED FOOD PRODUCTS [PDF]

This study examines the impact on export sales of various promotional strategies for branded food products in foreign markets. It is an empirical analysis using data obtained from organizations that administer the High Value Export Incentive Program ...
Brenes, Jose R., Henderson, Dennis R., Sheldon, Ian M.   +2 more
core   +1 more source

Multi-frequency, multi-messenger astrophysics with Swift. The case of blazars [PDF]

, 2015
During its first 10 years of orbital operations Swift dedicated approximately 11% of its observing time to blazars, carrying out more than 12,000 observations of ~1,600 different objects, for a total exposure time of over 25 million seconds.
Giommi, Paolo
core   +2 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

The CEOS Data Cube Portal: A User-Friendly, Open Source Software Solution for the Distribution, Exploration, Analysis, and Visualization of Analysis Ready Data [PDF]

There is an urgent need to increase the capacity of developing countries to take part in the study and monitoring of their environments through remote sensing and space-based Earth observation technologies.
Cherry, Andrew, Gowda, Sanjay, Killough, Brian, Rizvi, Syed R   +3 more
core   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Towards Sentinel-2 Analysis Ready Data: a Swiss Data Cube Perspective

IGARSS 2018 - 2018 IEEE International Geoscience and Remote Sensing Symposium, 2018
Earth Observations Data Cubes (EODC) are a new paradigm revolutionizing the way users can interact with Earth Observations (EO) data. They can provide access to large spatio-temporal data in analysis ready format. Systematic and regular provision of Analysis Ready Data (ARD) can significantly reduce the burden on EO data users by minimizing the time ...
Giuliani, Gregory, Chatenoux, Bruno, Honeck, Erica Cristine, Richard, Jean-Philippe   +3 more
openaire   +3 more sources

recount: A large-scale resource of analysis-ready RNA-seq expression data [PDF]

, 2016
Abstractrecountis a resource of processed and summarized expression data spanning nearly 60,000 human RNA-seq samples from the Sequence Read Archive (SRA). The associatedrecountBio-conductor package provides a convenient API for querying, downloading, and analyzing the data. Each processed study consists of meta/phenotype data, the expression levels of
Collado-Torres, Leonardo, Nellore, Abhinav, Kammers, Kai, Ellis, Shannon E., Taub, Margaret A., Hansen, Kasper D., Jaffe, Andrew E., Langmead, Ben, Leek, Jeffrey T.   +8 more
openaire   +2 more sources

Valuing Transgenic Cotton Technologies Using a Risk/Return Framework [PDF]

Stochastic Efficiency with Respect to a Function (SERF) is used to rank transgenic cotton technology groups and place an upper and lower bound on their value.
Bourland, Fred M., Bryant, Kelly J., Capps, Charles D., Greene, Jeremy K., Groves, Frank E., Nichols, Robert L., Reeves, Jeanne M., Studebaker, Glenn E., Tingle, Christopher H.   +8 more
core   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source