Results 101 to 110 of about 943,761 (315)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Kant’tan Kripke’ye: Analitiklik, Zorunluluk, A Priori İlişkisi

open access: yesFelsefe Dünyası
Bu çalışmada zorunluluğun, analitik ve a priori kavramlarıyla olan bağı çağdaş felsefedeki tartışmalarla ilgisi içerisinde incelenmeye çalışılacaktır. Bu doğrultuda ilk olarak Kant’ın yargı teorisinden hareketle yaptığı sınıflandırma ele alınacaktır.
Murat Fatih Yazıcı
doaj   +1 more source

Stratified Reduction of Singularities of Generalized Analytic Functions [PDF]

open access: green, 2022
Beatriz Molina-Samper   +2 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Austin i Quine o rozróżnieniu analityczne / syntetyczne? [PDF]

open access: yesArgument, 2014
Both John Langshaw Austin and Willard Van Orman Quine were critical of the traditional division of propositions into the two categories: analytic and synthetic. Their criticism has, however, a different character.
Jan Wawrzyniak
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A comparison of various analytic choice principles [PDF]

open access: green, 2019
Paul-Elliot Anglès d’Auriac   +1 more
openalex   +1 more source

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