Results 81 to 90 of about 2,427,544 (343)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Ergodic Transport Theory and Piecewise Analytic Subactions for Analytic Dynamics [PDF]
, 2012 We consider a piecewise analytic real expanding map $f: [0,1]\to [0,1]$ of degree $d$ which preserves orientation, and a real analytic positive potential $g: [0,1] \to \mathbb{R}$.
Lopes, Artur O. +2 more
core +1 more source
Toulmin’s “Analytic Arguments”
Informal Logic, 2012 Toulmin’s formulation of “analytic arguments” in his 1958 book, The Uses of Argument, is opaque. Commentators have not adequately explicated this formulation, though Toulmin called it a “key” and “crucial” concept for his model of argument ...
Ben Hamby
doaj
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Analytic Torsion of Z_2-graded Elliptic Complexes
, 2010 We define analytic torsion of Z_2-graded elliptic complexes as an element in the graded determinant line of the cohomology of the complex, generalizing most of the variants of Ray-Singer analytic torsion in the literature.
Mathai, Varghese, Wu, Siye
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Analytic vectors in continuous p-adic representations
, 2012 Given a compact p-adic Lie group G over a finite unramified extension L/Q_p let G_0 be the product over all Galois conjugates of G. We construct an exact and faithful functor from admissible G-Banach space representations to admissible locally L-analytic
Borel +10 more
core +2 more sources
Microplastics in urban water management
Technical Transactions, 2017 The paper is discussing microplastics in the effluent of wastewater treatment plants and other discharges from urban areas. The aim of the discussion is to expose the challenges related to sampling and detecting plastic particles in treated wastewater ...
Venghaus Daniel, Barjenbruch Matthias
doaj +1 more source
Applying speech technologies to assess verbal memory in patients with serious mental illness
npj Digital Medicine, 2020 Verbal memory deficits are some of the most profound neurocognitive deficits associated with schizophrenia and serious mental illness in general. As yet, their measurement in clinical settings is limited to traditional tests that allow for limited ...
Terje B. Holmlund +7 more
doaj +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source