Results 131 to 140 of about 13,244,184 (364)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Partial sums of certain analytic functions

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2001
The object of the present paper is to consider the starlikeness and convexity of partial sums of certain analytic functions in the open unit disk.
Shigeyoshi Owa
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Subordination Properties for Certain Analytic Functions

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2008
The purpose of the present paper is to derive a subordination result for functions in the class 𝐻∗𝑛(𝛼,𝜆,𝑏) of normalized analytic functions in the open unit disk 𝕌. A number of interesting applications of the subordination result are also considered.
A. A. Attiya, Nak Eun Cho, M. A. Kutbi
doaj   +1 more source

On the analytic functions

open access: yes, 2022
Let $Ω$ be a connected bounded domain on the complex plane, $S$ be its boundary, which is closed, star-shaped, $C^1$-smooth, and $H(Ω)$ is the set of analytic (holomorphic) in $Ω$ functions. The aim of this paper is to prove that an arbitrary $f\in L^1(S)$, satisfying the condition $\int_Sf(s)ds=0$, can be boundary value of an $f\in H(Ω)$.
openaire   +2 more sources

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Neighborhoods of Certain Multivalently Analytic Functions

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2012
We introduce and investigate two new general subclasses of multivalently analytic functions of complex order by making use of the familiar convolution structure of analytic functions.
Serap Bulut
doaj   +1 more source

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