Results 261 to 270 of about 13,660,663 (362)

Analytic and \(c\)-analytic functions

, 1969
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Analogs of the Prime Number Problem in a Shot Noise Suppression of the Soft-Reset Process. [PDF]

Nanomaterials (Basel)
Hirose Y.
europepmc   +1 more source

Computational benefit of smoothness: Parameterized bit-complexity of numerical operators on analytic functions and Gevrey’s hierarchy

, 2015
Akitoshi Kawamura, Norbert Müller, Carsten Rösnick, Martin Ziegler   +3 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Connectivity and function are coupled across cognitive domains throughout the brain. [PDF]

Netw Neurosci
Hiersche KJ, Saygin ZM, Osher DE.
europepmc   +1 more source

Loci of exactness for the real and imaginary parts of truncated Taylor series of analytic functions

Gaëtan Hello
openalex   +1 more source

On the zeros of polynomials and related analytic functions

, 1998
Abdul Aziz, W. M. Shah
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Non-trivial Fixed Point of a ψ d 4 Fermionic Theory, II: Anomalous Exponent and Scaling Operators. [PDF]

Commun Math Phys
Giuliani A, Mastropietro V, Rychkov S, Scola G.   +3 more
europepmc   +1 more source