Results 61 to 70 of about 16,514,849 (251)

Optimization of small-scale sample preparation for high-throughput OpenArray analysis

open access: yes, 2021
OpenArray is one of the most high-throughput qPCR platforms available but its efficiency can be limited by sample preparation methods that are slow and costly.
Abraham, Neeta A.   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Atomic characterization of Si nanoclusters embedded in SiO2 by atom probe tomography

open access: yesNanoscale Research Letters, 2011
Silicon nanoclusters are of prime interest for new generation of optoelectronic and microelectronics components. Physical properties (light emission, carrier storage...) of systems using such nanoclusters are strongly dependent on nanostructural ...
Gourbilleau Fabrice   +3 more
doaj  

Culturally responsive assessment practices in ethnic minority semi-boarding primary schools in Vietnam: a mixed-methods study

open access: yesFrontiers in Education
This study examines the implementation and determinants of culturally responsive assessment (CRA) in ethnic minority semi-boarding primary schools in Vietnam. Four structured questionnaires were distributed to school leaders (n = 123), teachers (n = 406),
Lam Thuy Duong, Phi Dinh Khuong
doaj   +1 more source

NEW SAMPLE PREPARATION METHODS FOR PROTEOMIC

open access: yes, 2011
The complexity of proteomes brings great challenge to the in-depth study on proteomics, due to the great number of proteins in a sample, the wide dynamic change in abundance, different physical and chemical properties, changes in spaces and with time ...
待补充, 张玉奎
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Rock Sample Surface Preparation Influences Thermal Infrared Spectra

open access: yes, 2020
Data of Rost, E.; Hecker, C.; Schodlok, M.C.; Van der Meer, F.D. Rock Sample Surface Preparation Influences Thermal Infrared Spectra.
Rost, MSc E (Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente) ORCID=0000-0003-3016-0016
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Green Analytical Chemistry: Current Status and Future Perspectives in Sample Preparation

open access: yes
Green Analytical Chemistry: Current Status and Future Perspectives in Sample Preparation presents the state-of-the-art in the field of GAC sample preparation procedures.
Locatelli, Marcello, Kaya, Savaş
core   +1 more source

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