Response to Freedman and Schrack: drawing inferences about Medicare mortality from the National Health and Aging Trends Study. [PDF]
Gill TM, Liang J, Davis-Plourde K.
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Machine learning-based model for triage-stage prediction of emergency department disposition. [PDF]
Yoshimura K, Moriguchi T.
europepmc +1 more source
Series Rearrangements and Analytic Sets [PDF]
Lorentz, G. G., Zeller, K.
openaire +3 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Construction of an Interpretive Structural Model-Analytic Network Process model for preschool children's drowning risk factors based on the Haddon matrix. [PDF]
Ma F, Luo D, Liu H, Zhao G.
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Multi-Omics Biomarkers From Variant to Clinic: A Systematic Review and Meta-Analysis of Evidence, AI/ML, Governance, Equity, and Real-World Implementation Across Global Health Systems. [PDF]
Das N.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
How to Improve the Reliability of Aperiodic Parameter Estimates in M/EEG: A Method Comparison. [PDF]
Kałamała P +6 more
europepmc +1 more source

