Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Letter to the Editor: Less can be more, rethinking colonic biopsy strategies for microscopic colitis in the era of green endoscopy. [PDF]
Agrawal H, Gupta N.
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Benchmarking the Plasmon-Pole and Multipole Approximations in the Yambo Code Using the GW100 Data Set. [PDF]
Bonacci M +6 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Response to the Letter to the Editor Regarding "Fusion Construct Length Is Associated with Increased Risk of Delayed Reoperation Following Cervical and Lumbar Fusion". [PDF]
Rahmani R +7 more
europepmc +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Baseline amyloid burden and global cognitive change during a home-based tDCS protocol in late-life depression: an exploratory single-arm study. [PDF]
Li Y, Park J, Park JY, Kim WJ.
europepmc +1 more source
Maternal Distress Due to the COVID-19 Pandemic and Changes in Young Children's Behavior. [PDF]
Martin A +5 more
europepmc +1 more source

