Results 131 to 140 of about 105,341 (258)

Feasibility, image quality, and analytic usability of mobile 64 mT ultra-low-field MRI for infant brain imaging at 3 and 12 months in southern Malawi. [PDF]

J Magn Reson Open
Vokhiwa M, Chetcuti K, Lange F, Bourke NJ, Randall L, Greenstein S, Seal M, Beare R, Hussain A, Rao P, Ljungberg E, Padormo F, Rogers J, Torelli P, Williams S, Jones DK, Deoni SCL, Pasricha SR, Phiri KS, Umar E, Unity Consortium.   +20 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Beyond the Task List: Considering the Affective and Social Context of Analytic Work in Undergraduate Research. [PDF]

CBE Life Sci Educ
Wang R, Li X.
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Interpretable machine learning for depression symptom classification in NHANES: Performance in a curated high-confidence corpus and the full survey population. [PDF]

IBRO Neurosci Rep
Salimi O, Ghahramani Z, Zenouz MT, Heidari M, Amini A, Nouroozi F, Fathi M, Tavasol A, Bateni MR.   +8 more
europepmc   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

An Exploratory Stability Selection (ESS) framework for robust predictor discovery: An application to physical resilience in aging populations. [PDF]

Exp Gerontol
Ashner MC, Kraus VB, Whitson HE, Simon CB, Huebner JL, Bareja A, Perfect CR, Pietrosimone L, Hall KS, Colón-Emeric CS, Peskoe SB.   +10 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Single-shot detection limits of quantum illumination with multi-qudit states. [PDF]

Sci Rep
Kang S, Jo Y, Kim J, Kim Z, Kim DY, Lee SY.   +5 more
europepmc   +1 more source