Results 151 to 160 of about 166,170,401 (203)

Flow-Based Surrogates for High-Dimensional Likelihoods in Experimental Neutrino Physics

Baz ME, Giannessi L, Blanchet A, Sánchez F.   +3 more
europepmc   +1 more source

An Approximate Bayesian Approach to Optimal Input Signal Design for System Identification. [PDF]

Entropy (Basel)
Bania P, Wójcik A.
europepmc   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Quasisymmetries of finitely ramified Julia sets. [PDF]

Math Ann
Belk J, Forrest B.
europepmc   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Algebraic overshear density property. [PDF]

Beitr Algebra Geom
Andrist RB, Kutzschebauch F.
europepmc   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

Carbon-phosphorus exchange rate constrains density-speed trade-off in arbuscular mycorrhizal fungal growth. [PDF]

Proc Natl Acad Sci U S A
Bisot C, Galvez LO, Kahane F, van Son M, Turcu B, Broekman R, Lin KK, Bontenbal P, Winter MK, Kokkoris V, West SA, Godin C, Kiers ET, Shimizu TS.   +13 more
europepmc   +1 more source

EndoTac: An Endoscopic Camera‐Based Tactile Sensor with High Sensitivity for Minimally Invasive Surgery

Advanced Science, EarlyView.
EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang, Nicolas Raison, Xuyang Zhang, Aijia Yang, Lukas Lindenroth, Shan Luo   +5 more
wiley   +1 more source

Generic algebraic conditions for the occurrence of switch-like behavior of a chemical kinetic system of the hypoxia pathway. [PDF]

J Biol Phys
Vanhaelen Q.
europepmc   +1 more source