Results 101 to 110 of about 5,620,047 (250)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Highly Accurate Analytical Approximate Solution to a Nonlinear Pseudo-Oscillator

open access: yes, 2017
A second-order Newton method is presented to construct analytical approximate solutions to a nonlinear pseudo-oscillator in which the restoring force is inversely proportional to the dependent variable.
Weijia Liu, C.W. Lim, Baisheng Wu
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Fractional calculus model for damped Mathieu equation: approximate analytical solution

open access: yes, 2012
The classical damped Mathieu differential equation was firstly introduced by Mathieu in 1868 to determine the vibration modes of a stretched membrane having an elliptical clamped boundary.
Doaa M M Elsayed   +2 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Approximate analytical solutions to conformable modified Burgers equation using homotopy analysis method [PDF]

open access: yes, 2018
In this paper the authors aspire to obtain the approximate analytical solution of Modified Burgers Equation with newly defined conformable derivative by employing homotopy analysis method (HAM)
Tasbozan, Orkun, Kurt, Ali
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

An approximate solution for a generalized Hirota-Satsom coupled (Kdv) equation [PDF]

open access: yes, 2017
In this paper the Homotopy Analysis Method (HAM), is applied to find the approximate solution of Hirota-Satsuma coupled (KdV) equations, which don't need a small parameter for solution.
H.A. Wahab   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Approximate Analytical Solution of Soil Temperature in Soil Warming [PDF]

open access: yes
To get a theoretical basis for the dynamic characteristics off a soil warming process, an approximate solution of soil temperature at the unsteady state was derived analytically.
90115246   +5 more
core  

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