Results 161 to 170 of about 421,933 (309)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Green Analytical Chemistry: Current Status and Future Perspectives in Sample Preparation

Green Analytical Chemistry: Current Status and Future Perspectives in Sample Preparation presents the state-of-the-art in the field of GAC sample preparation procedures.
Locatelli, Marcello, Kaya, Savaş
core   +1 more source

Artificial Intelligence in Analytical Chemistry: Towards Yet Undiscovered Opportunities. [PDF]

Anal Chem
Nowak PM.
europepmc   +1 more source

Editorial: Innovators in analytical chemistry. [PDF]

Front Chem, 2023
Bala C, Jaffrezic-Renault N, Massolini G, Valenti G.   +3 more
europepmc   +1 more source

Retracted: Blasting Law of Liquid CO2 Phase Change in Coal Mine Based on Numerical Simulation

International Journal of Analytical Chemistry, 2023
International Journal of Analytical Chemistry
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

In Situ Analytical Chemistry Laboratory for the Exobiology Extant Life Surveyor. [PDF]

ACS Meas Sci Au
Drevinskas T, Cable ML, Stenner C, Gardner AS, Paton M, Malaska MJ, Cruz S, Rieber R, Etheredge R, Robinson M, Ono M, Mora MF, Bagshaw EA, Prior-Jones MR, Ferreira Santos MS, Noell AC, Willis PA.   +16 more
europepmc   +1 more source

Retracted: Prediction of Dissolved Oxygen Concentration in Sewage Treatment Process Based on Data Recognition Algorithm

International Journal of Analytical Chemistry, 2023
International Journal of Analytical Chemistry
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Continuous sample drop flow microextraction: a versatile and green microextraction tool in analytical chemistry. [PDF]

RSC Adv
Yaqoub AR, Mohammed Ameen SS, Abdullah AH, Omer KM.   +3 more
europepmc   +1 more source