Results 241 to 250 of about 333,858 (264)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The development of Analytical Chemistry in Brazil: retrospective and expectations
, 2003 Zagatto Elias A. G., Sá Sandra M. O.
openalex +1 more source
Analytical chemistry and measurement science: (What has DOE done for analytical chemistry. )
, 2008 W. D. Shults
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Steven P Rowe, Martin G Pomper
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A reticular chemistry guide for the design of periodic solids
Nature Reviews Materials, 2021Hao Jiang +2 more
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Machine learning in combinatorial polymer chemistry
Nature Reviews Materials, 2021Adam J Gormley, Michael A Webb
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Biomedicine Meets Fenton Chemistry
Chemical Reviews, 2021Zhongmin Tang, Peiran Zhao, Yanyan Liu
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