Results 71 to 80 of about 1,156,104 (297)

Moment Closure - A Brief Review

open access: yes, 2015
Moment closure methods appear in myriad scientific disciplines in the modelling of complex systems. The goal is to achieve a closed form of a large, usually even infinite, set of coupled differential (or difference) equations. Each equation describes the
A Bátkai   +114 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Retracted: Application of Carbon Fiber Cement-Based Composites in Improving Construction Durability

open access: yesInternational Journal of Analytical Chemistry, 2023
International Journal of Analytical Chemistry
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Retracted: Influence of Nano-Cutting Fluid in New Cutting and Forming Processes on Heat Transfer Performance of Mechanical Engineering

open access: yesInternational Journal of Analytical Chemistry, 2023
International Journal of Analytical Chemistry
doaj   +1 more source

Chemometrics and model fitting in analytical chemistry [PDF]

open access: yes, 2005
University of Technology, Sydney. Dept. of Chemistry, Materials and Forensic Science.The aims of this project are to investigate the ability of advanced mathematical techniques and their contribution to the analysis of complex situations in analytical ...
Foot, MJ
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Retracted: Mechanical Performance Test and Numerical Simulation Analysis of Building Steel Plate and Concrete Composite Structure

open access: yesInternational Journal of Analytical Chemistry, 2023
International Journal of Analytical Chemistry
doaj   +1 more source

From Micro to Nano Biphasic Calciumphosphate/Poly-Dl-Lactide-Co- Glycolide Composite Biomaterials for Hard Tissue Reconstruction [PDF]

open access: yes, 2007
Poster presented at the Pittcon 2007 - Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, February 25 – March 2 ...
Ignjatović, Nenad, Uskoković, Dragan
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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