Results 71 to 80 of about 1,156,104 (297)
Moment Closure - A Brief Review
Moment closure methods appear in myriad scientific disciplines in the modelling of complex systems. The goal is to achieve a closed form of a large, usually even infinite, set of coupled differential (or difference) equations. Each equation describes the
A Bátkai +114 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Retracted: Application of Carbon Fiber Cement-Based Composites in Improving Construction Durability
International Journal of Analytical Chemistry
doaj +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
International Journal of Analytical Chemistry
doaj +1 more source
Chemometrics and model fitting in analytical chemistry [PDF]
University of Technology, Sydney. Dept. of Chemistry, Materials and Forensic Science.The aims of this project are to investigate the ability of advanced mathematical techniques and their contribution to the analysis of complex situations in analytical ...
Foot, MJ
core
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
International Journal of Analytical Chemistry
doaj +1 more source
From Micro to Nano Biphasic Calciumphosphate/Poly-Dl-Lactide-Co- Glycolide Composite Biomaterials for Hard Tissue Reconstruction [PDF]
Poster presented at the Pittcon 2007 - Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, February 25 – March 2 ...
Ignjatović, Nenad, Uskoković, Dragan
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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

