Results 161 to 170 of about 293,293 (256)

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Online Coupling of Field-Flow Fractionation with Raman Microspectroscopy Enables the Advanced Study of Nanoplastics Directly in Food. [PDF]

Anal Chem
Giordani S, Huber MJ, Jüngling IS, Zattoni A, Roda B, Reschiglian P, Marassi V, Ivleva NP.   +7 more
europepmc   +1 more source

Editorial: Celebrating the 20th Anniversary of Pakistan Journal of Analytical & Environmental Chemistry

, 2020
Najma Memon
openalex   +1 more source

A Phase 1, Randomized, Open‐Label, Parallel Group Study to Evaluate the Relative Bioavailability and Safety of Subcutaneous Bepirovirsen when Delivered from a Vial or Prefilled Syringe Fitted with a Safety Syringe Device in Healthy Adult Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bepirovirsen, an antisense oligonucleotide in development for the treatment of chronic hepatitis B virus (HBV) infection, is administered from glass vials as a subcutaneous (SC) injection by healthcare professionals (HCPs). A ready‐to‐use prefilled syringe (PFS) assembled with a safety syringe device (SSD) has been developed to make ...
Amir S. Youssef, Poonam Shah, Maxwell Hu, Helene Plein, Abhishek Roy, Ravi Sharma, Sarah Mole, Magdalena Blazejczyk, Wendy Cross, Brian Spears, Samuel Pak, Rejbinder Kaur, Robert Elston, Dickens Theodore, Marjan Hezareh, Ahmed Nader   +15 more
wiley   +1 more source

Chemometric-assisted UV-Vis spectrophotometric method for the simultaneous quantification of triple anthelmintics in veterinary pharmaceuticals. [PDF]

Sci Rep
Al-Farhan BS, Eldin GMG.
europepmc   +1 more source

Open Journal of Analytical and Bioanalytical Chemistry

, 2019

openalex   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

Clinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich, Meenakshi Srinivasan, Yu Liu Ho, Sandra A.G. Visser, Geraldine Ferron‐Brady, Georgios Vlasakakis   +5 more
wiley   +1 more source

Integrating In Vitro Analytics for Improved Antibody-Drug Conjugate Candidate Selection. [PDF]

Cancers (Basel)
Del Solar V, Saleh A, Di Tacchio A, Becciolini LS, Kang GD, Jackowska B, Hu Y, Gong C, Zhang A, Hostetler L, Lee M, Khan AH, Mitra A, Ahmed M, Tickle D, Vijayakrishnan B.   +15 more
europepmc   +1 more source

International Journal of Environmental Analytical Chemistry

, 2011
Walter Ignácio Gonçalves dos Santos, Dannuza Dias Cavalcante, Hadla S. Ferreira, Cesário Francisco das Virgens, Aline Rocha Borges, Silva, Márcia Siqueira de Carvalho, Andresa Lourenço da, Maria Carla Bulhão de Queirós Andrade VALE, Walter Ignácio Gonçalves dos Santos, Dannuza Dias Cavalcante, Hadla S. Ferreira, Cesário Francisco das Virgens, Aline Rocha Borges, Silva, Márcia Siqueira de Carvalho, Andresa Lourenço da, Maria Carla Bulhão de Queirós Andrade VALE   +13 more
openalex   +1 more source

Optimizing Body Size‐Based Dosing Approaches for Antibody–Drug Conjugates

Clinical Pharmacology &Therapeutics, EarlyView.
Optimized dosing precision of antibody–drug conjugates (ADCs) remains challenging due to narrow therapeutic indices, efficacious doses near the maximum tolerated dose, and substantial interindividual variability in exposure. Body size‐based dosing can reduce exposure variability when the allometric scaling exponent for clearance α = 1 but may over‐ or ...
Andrew B. SyBing, Diane D. Wang
wiley   +1 more source