Results 211 to 220 of about 885,457 (308)

Open Journal of Analytical and Bioanalytical Chemistry

, 2019

openalex   +1 more source

Green "turn-off" luminescent nanosensor for the sensitive analysis of finerenone in various matrices: application of recent greenness assessment techniques. [PDF]

RSC Adv
Ali MB, Abdel-Raoof AM, Elbardisy HM, Omran GA, Ragab MA, Morshedy S.   +5 more
europepmc   +1 more source

Electronic Patient File‐Embedded Model‐Informed Precision Dosing Compared with Physician Dosing of Tacrolimus in Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers, Pieter Annaert, Borefore Jallah, Maarten Naesens, Maxine Teuns, Annouschka Laenen, Ruben Faelens   +6 more
wiley   +1 more source

Chemical Bonding: A First-Year Seminar Series that Enhances Chemistry Majors' Perceptions of Chemistry Subdisciplines. [PDF]

ACS Omega
Saenger SL, Nennig HT, Winters J, Wainman JW.   +3 more
europepmc   +1 more source

Large Language Models for Clinical Trial Protocol Assessments

Clinical Pharmacology &Therapeutics, EarlyView.
The purpose was to evaluate the utility of large language models (LLMs) for reviewing the statistical analysis plan (SAP) and pharmacokinetics–pharmacodynamics (PK–PD) components of clinical trial protocols. Clinical trial protocols and SAPs were obtained from clinicaltrials.gov for a testbed of 15 small‐molecule drugs, biologics, and global antibiotic
Euibeom Shin, Amruta Gajanan Bhat, Murali Ramanathan   +2 more
wiley   +1 more source

Sustainable HPLC method for simultaneous determination of Cefazolin, Sulfadimidine, and Marbofloxacin residues in milk. [PDF]

Sci Rep
Hammad SF, Rabee M, Abozeid RA, Elagamy SH.   +3 more
europepmc   +1 more source

The Rising Misuse of Pharmacovigilance Reporting Systems: A Threat to Evidence‐Based Medicine

Clinical Pharmacology &Therapeutics, EarlyView.
In recent years, different national and international regulatory authorities, notably the FDA, have made their adverse event repositories publicly available, offering user‐friendly dashboards. This has led to a large increase in low‐quality, poorly reported research using adverse event reporting databases (e.g., FDA’s Adverse Event Reporting System ...
Charles Khouri, Alex Hlavaty, Michele Fusaroli, Nitin Joshi, Francesco Salvo, Andrew Bate, Antoine Pariente, Emanuel Raschi   +7 more
wiley   +1 more source

Retracted: The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression

Journal of Analytical Methods in Chemistry, 2020
Journal of Analytical Methods in Chemistry
doaj   +1 more source

Fresenius' Journal of Analytical Chemistry

, 1999
M. Schilling, G. Voigt, Tania M. Tavares, D. Klockow, M. Schilling, G. Voigt, Tania M. Tavares, D. Klockow   +7 more
openalex   +1 more source

Optimizing Body Size‐Based Dosing Approaches for Antibody–Drug Conjugates

Clinical Pharmacology &Therapeutics, EarlyView.
Optimized dosing precision of antibody–drug conjugates (ADCs) remains challenging due to narrow therapeutic indices, efficacious doses near the maximum tolerated dose, and substantial interindividual variability in exposure. Body size‐based dosing can reduce exposure variability when the allometric scaling exponent for clearance α = 1 but may over‐ or ...
Andrew B. SyBing, Diane D. Wang
wiley   +1 more source