Results 251 to 260 of about 885,457 (308)

Scalp‐negative medial temporal interictal epileptic discharges alter large‐scale brain networks: A simultaneous high‐density electroencephalographic and intracranial electroencephalographic study

open access: yesEpilepsia, EarlyView.
Abstract Objective Interictal epileptiform discharges (IEDs) observed on scalp electroencephalography (EEG) serve as a diagnostic hallmark of epilepsy. However, only a small fraction of IEDs recorded by intracranial EEG (iEEG) are detectable on the scalp; the vast majority remain invisible on scalp recordings.
Nicolas Roehri   +7 more
wiley   +1 more source

Deciphering the intermolecular interactions between G-quadruplex (G4)-forming sequences. [PDF]

open access: yesNucleic Acids Res
Xia J   +8 more
europepmc   +1 more source

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens   +8 more
wiley   +1 more source

Altered neurostructural development in magnetic resonance imaging‐negative pediatric epilepsy: A large‐scale multicenter study of 1919 children

open access: yesEpilepsia, EarlyView.
Abstract Objective Addressing the poorly understood impact of pediatric epilepsy on neurodevelopment, this large‐scale study delineates age‐ and sex‐stratified neurostructural trajectories in magnetic resonance imaging (MRI)‐negative pediatric epilepsy to identify periods of maximal developmental divergence from healthy controls.
Yingfan Wang   +10 more
wiley   +1 more source

Are single‐item global rating scales the same, better, or worse than multi‐item scales in epilepsy: A scoping review and meta‐analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective To examine the performance of single‐item global ratings (SIGRs) and multi‐item scales (MISs) in epilepsy research, and assess the influence of diverse constructs, study designs, and statistical methods. Methods Systematic scoping review following Preferred Reporting Items for Systematic reviews and Meta‐Analyses (PRISMA) and Joanna ...
Ann Subota   +2 more
wiley   +1 more source

Behavioral and epileptic phenotypes in a CHD2‐related developmental delay model

open access: yesEpilepsia, EarlyView.
Abstract Objective Heterozygous loss‐of‐function mutations in the CHD2 gene, encoding chromodomain helicase DNA‐binding protein 2, are associated with severe childhood onset epilepsy, global developmental delay, and autistic features. Animal models that accurately recapitulate human phenotypes are crucial for understanding rare neurodevelopmental ...
Anat Mavashov   +10 more
wiley   +1 more source

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