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Analytical eco‐scale and quality by design‐oriented liquid chromatography method for simultaneous quantification of metoprolol succinate, telmisartan, and cilnidipine in their fixed‐dose combination

Separation Science Plus, 2021
Abstract A new combination of metoprolol succinate, telmisartan, and cilnidipine is recently approved to treat hypertension effectively. A reversed‐phase liquid chromatography method was developed to quantify the said compounds, combining analytical eco‐scale and quality‐by‐design approach. The former one revealed
Sagar Panda
exaly   +2 more sources

An eco-friendly and alternative method of forced degradation of fluoroquinolone drugs by microwave irradiation: a new application for analytical eco-scale

Journal of Microwave Power and Electromagnetic Energy, 2018
AbstractForced degradation studies are essential to determine the drug stability, elucidate the main degradation routes, and monitor the degradation products in qualitative/quantitative terms. Over the years, the pharmaceutical industry has been using a traditional and conventional method that employs a stove as the heating source; this requires a ...
Gilberto L B Aquino, Lucas Danilo Dias
exaly   +2 more sources

Comparative Studies of GAC Metric Tools AGREE, Analytical Eco-Scale, BAGI and WAC RGB Model to Determine Atorvastatin in Pharmaceuticals

Critical Reviews in Analytical Chemistry
Atorvastatin has promising effects on hyperlipidemia disease and illness. Therefore, following the twelve green analytical chemistry principles, acquiring productive analytical methodologies to determine the drugs is essential. Several analytical methods, such as ultraviolet spectrophotometry, high-performance liquid chromatography, ultra-pressure ...
Sk Manirul Haque
exaly   +3 more sources

Application of NEMI, Analytical Eco-Scale and GAPI tools for greenness assessment of three developed chromatographic methods for quantification of sulfadiazine and trimethoprim in bovine meat and chicken muscles: Comparison to greenness profile of reported HPLC methods

Microchemical Journal, 2020
Abstract Employing green analytical chemistry approaches to newly developed methods has extremely gained the interest of the analytical community and was intensely established in the past few years. The utilized solvents as well as the amount of produced waste have the chief impact on evaluating the greenness of the method.

exaly   +2 more sources

Deep eutectic solvent as a novel disperser in dispersive liquid-liquid microextraction based on solidification of floating organic droplet (DLLME-SFOD) for preconcentration of steroids in water samples: Assessment of the method deleterious impact on the environment using Analytical Eco-Scale and Green Analytical Procedure Index

Microchemical Journal, 2019
Abstract Herein, we seek clues to investigate the effectiveness of deep eutectic solvent (DES) as a novel dispersive solvent in DLLME-SFOD for the enrichment of nine steroids in water for the first time. The novel DLLME-SFOD method is premised on using 2-dodecanol as extractant and DES (tetrabutylammonium bromide: acetic acid) as a dispersive solvent.
Kuniyoshi Shimizu, Asmaâ Kamal El-Deen
exaly   +2 more sources

Fast detection of apricot product frauds by added pumpkin via planar chromatography and chemometrics: Greenness assessment by analytical eco-scale

Food Chemistry, 2022
The European Commission requires that fruit products distributed on the market meet standards of high quality and authenticity. For the quality assessment of apricot products susceptible to food fraud, an environmentally friendly, simple and cost-effective analytical profiling was developed by high-performance thin-layer chromatography multi-imaging ...
Ristivojević, Petar   +4 more
openaire   +3 more sources

Green and Smart Quantitative Quality Control for Veterinary Mixture of Ivermectin and Clorsulon: Ecological Evaluation of Spectral Analyses via Analytical Eco-Scale, Green Analytical Procedure Index, and Analytical GREEnness Metric Approaches

Journal of AOAC International, 2023
Abstract Background The global financial market is still highly threatened by bovine fasciolosis, a parasitic infection that targets cattle, mainly in tropical regions. Binary combination of ivermectin (IVER) and clorsulon (CLO), in challenging concentration ratios, is typically indicated for ...
Miranda F Kamal   +3 more
openaire   +2 more sources

Green analytical profiling of Teucrium chamaedrys L. using natural deep eutectic solvents and planar chromatography: a greenness assessment by the National Environmental Methods Index and analytical eco-scale

JPC – Journal of Planar Chromatography – Modern TLC, 2023
Owing to the use of large volumes of toxic solvents and reagents, green analytical methods have gained increasing importance in natural product research. Herein, a green approach is proposed using the natural deep eutectic solvents (NADES) for the extraction and separation of phenols from Teucrium chamaedrys by use of an ecofriendly high-performance ...
Mila Lazović   +5 more
openaire   +2 more sources

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