Results 51 to 60 of about 12,899,175 (299)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Comparative Study of Biomethane Purification Process using Analytical Hierarchy Process

Jurnal Teknik Kimia dan Lingkungan
The selection of purification technology for upgrading biogas to biomethane involves complex considerations, as each technology -such as pressure swing adsorption (PSA), membrane separation (MS), or chemical absorption (CA) - offers distinct advantages ...
Theodora Mega Putri, Berlian Simanjuntak, Eyunike Rumahorbo, Kristy Panggabean   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Analysis of Productivity Measurement in CPO Production Using OMAX Method

Spektrum Industri: Jurnal Ilmiah Pengetahuan dan Penerapan Teknik Industri, 2023
The primary focus of this research revolves around the measurement of productivity and the factors that impact Crude Palm Oil (CPO) production which currently faces challenges in assessing whether existing productivity falls into the 'satisfactory ...
Ade Dwi sakti, Misra Hartati, Muhammad Nur, Harpito Harpito   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

ANALYTICAL HIERARCHY PROCESS IN THE ASSESSMENT OF PROJECT VARIANTS

Research on Enterprise in Modern Economy Theory and Practice, 2018
The aim of the article is to present the possibilities of using the AHP method in the project process. The first part of the article discusses the theoretical assumptions of the method of AHP (analytic hierarchy process).
Paweł Cabała
doaj   +1 more source

Applying the Analytic Hierarchy Process to an Institutional Repository Collection [PDF]

, 2018
This paper applies the analytic hierarchy process to evaluate collection development strategies for an institutional ...
Karen Harker, Pamela Andrews, Harker, Karen, Ana Krahmer, Andrews, Pamela, Krahmer, Ana   +5 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Metode Analytical Hierarchy Process Dalam Menentukan Pemilihan Desa Terbaik

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2019
The purpose of this study is to make decisions using the Analytical Hierarchy Prosess (AHP) method in determining the best village. Criteria for determining the best village; namely Community Economy, Public Health, Education, Security and Order and ...
Tri Rahayu, Erly Krisnanik, Bayu Hananto
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source