Results 111 to 120 of about 1,208,813 (315)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analytical Method Validation Characteristics.

, 2017
Analytical Method Validation Characteristics.
Pelagia Anastasiadou (3684904), Kyriaki Machera (580995), Konstantinos M. Kasiotis (3684907), Antonis Papadopoulos (3684910)   +3 more
core   +1 more source

Development and validation of a novel analytical method to quantify aflatoxins in baby food samples by employing dispersive solid phase extraction with multi-walled carbon nanotubes

, 2020
A new method for the quantification of four aflatoxins (AFB1, AFB2, AFG1, and AFG2) in baby food samples is described herein. In this method, the extraction/cleanup step was performed by using multi-walled carbon nanotubes as a sorbent material in a ...
Rodinei Augusti, Fernando Diniz Madureira, Eugenia de Azevedo Vargas, Lucas Pinto da Silva, Adriana Ferreira Faria   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Selective determination of aluminum bound with tannin in tea infusion

, 2005
In this study, an analytical method for indirect measurement of Al bound with tannin in tea infusion was studied. This method utilizes the ability of the tannins to precipitate with protein.
Erdemoglu, Sema B.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Chromatographic Data Segmentation Method : A Hybrid Analytical Approach for the Investigation of Antiviral Substances in Medicinal Plant Extracts

, 2019
The methodology described in this article will significantly reduce the time required for understanding the relations between chromatographic data and bioactivity assays.
Lelesius, Raimundas,, Telksnys, Laimutis,, Tiso, Nicola,, Drevinskas, Tomas,, Hjertén, Stellan,, Karpovaite, Agneta,, Ragazinskiene, Ona,, Stankevicius, Mantas,, Salomskas, Algirdas,, Mickiene, Ruta,, Maruska, Audrius,   +10 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Analytical calculation approach for rocket nose cone structure with orthotropic material

Aviation
The Authors of this research developed an analytical calculation method to estimate the strength of nose cone structures made of orthotropic materials, which were crucial components in aircraft and spacecraft.
Arief Budi Sanjaya, Haryadi Abrizal, Muhammad Dito Saputra, Rahmat Alfi Duhri, Muhamad Hananuputra Setianto, Ahmedi Asraf, Hendra Gantina   +6 more
doaj   +1 more source

Lectures on the Mathematical Method in Analytical Economics

, 2018
Early but still useful contribution to the science of mathematical economics explores the Leontif model and the technological basis of production, theory of business cycles, and neoclassical equilibrium theory.
Schwartz, Jacob T.
core