Results 231 to 240 of about 3,278,763 (292)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Caution in causal interpretation of ecological analyses of life expectancy during COVID-19 in Brazil. [PDF]

Lancet Reg Health Am
Queiroga M, Cardoso F, Medeiros Parente RC.   +2 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Assessment of the effectiveness of protein in critical illness: the role of statistical shortcomings in explaining discrepancies between observational studies and randomized controlled trials. [PDF]

Crit Care
Neuberger M, Hartl WH.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Reliable Quantification of Powdered Ginger Adulteration by Vis-NIR Spectroscopy and Chemometrics. [PDF]

Molecules
Amine R, Sánchez PF, Kharkhour H, El-Laghdach A, Palma M, Azaroual L.   +5 more
europepmc   +1 more source

Wave Propagation in a Periodically Layered Medium, Taking into Account the Effect of Microstructure Size: A Tolerance Modelling Method. [PDF]

Materials (Basel)
Jędrysiak J.
europepmc   +1 more source

Hyperspectral Imaging-Based Rapid Assessment of Chinese Yam Quality for Dried Slice Processing. [PDF]

Foods
Shen T, Yang Y, Yang D, Chen C, Zhai X, Li Z, Zhang J, Zhang R, Wang T, Huang X, Shi J.   +10 more
europepmc   +1 more source

Multilevel Determinants of Acromiohumeral Distance Within a Systems-Based Functional Morphology Framework and Their Implications for Personalized Neuromusculoskeletal Modelling. [PDF]

J Funct Morphol Kinesiol
Arráez-Aybar LA, García-de-Pereda-Notario CM, Palomeque-Del-Cerro L, Montoya-Miñano JJ.   +3 more
europepmc   +1 more source

Polymer-Enabled Additive Manufacturing for Personalized Drug Delivery and Diagnostic Platforms: Materials, Architectures, Quality Control and Clinical Translation. [PDF]

Polymers (Basel)
Pandian P, Sethuraman V, Shukla AK, Nagappan A.   +3 more
europepmc   +1 more source