Results 111 to 120 of about 703,453 (308)

Comparison of diffuse correlation spectroscopy analytical models for measuring cerebral blood flow in adults. [PDF]

J Biomed Opt, 2023
Zhao H, Sathialingam E, Cowdrick KR, Urner T, Lee SY, Bai S, Akbik F, Samuels OB, Kandiah P, Sadan O, Buckley EM.   +10 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Analytical quasi maximum likelihood inference in multivariate volatility models

Quasi maximum likelihood estimation and inference in multivariate volatility models remains a challenging computational task if, for example, the dimension is high.
Hafner, C.M., Herwartz, H.
core  

Analytical Models for Pose Estimate Variance of Planar Fiducial Markers for Mobile Robot Localisation. [PDF]

Sensors (Basel), 2023
Adámek R, Brablc M, Vávra P, Dobossy B, Formánek M, Radil F.   +5 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of water table on hierarchically nested groundwater flow system

Journal of Groundwater Science and Engineering
Water table configuration gives rise to hierarchically nested groundwater flow systems. However, there remains a lack of comprehensive understanding regarding the controlling factors of water table and its impact on flow systems.
Jun Zhang, Rong-zhe Hou, Kun Yu, Jia-qiu Dong, Li-he Yin   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Comparison of Different Configurations for a Shoreline Pond Electrode Station in the Case of an HVDC Transmission System—Part II: Electric Field Study for Frames of Non-Linear Novel Electrode Arrangement Based on a Simplified Analytical Model

Applied Sciences
According to CIGRE, the usual arrangement of electrodes in a shoreline electrode station for HVDC interconnections is straight with the following form: forming straight frames with the electrodes at equal distances and placing the frames parallel to the ...
George J. Tsekouras, Vasilios P. Androvitsaneas, Vassiliki T. Kontargyri, John M. Prousalidis, Costantinos D. Tsirekis, Konstantinos Leontaritis, John C. Alexandris, Fotis D. Kanellos, Panagiota M. Deligianni, Panagiotis A. Kontaxis, Antonios X. Moronis   +10 more
doaj   +1 more source

Analytical models for external photon beam radiotherapy out-of-field dose calculation: a scoping review. [PDF]

Front Oncol, 2023
Benzazon N, Colnot J, de Kermenguy F, Achkar S, de Vathaire F, Deutsch E, Robert C, Diallo I.   +7 more
europepmc   +1 more source