Results 41 to 50 of about 622,330 (261)
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Dependencies among Architectural Views Got from Software Requirements Based on a Formal Model
A system architect has software requirements and some unspecified knowledge about a problem domain (e.g., an enterprise) as source information for assessment and evaluation of possible solutions and getting the target point, a preliminary software design.
Osis Janis +3 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
The stability of deep soft rock tunnels under seepage conditions is of particular concern. Aiming at thoroughly discussing seepage actions and their consequences on the support schemes of such structures, the host rocks of the Weilai Tunnel situated in ...
Wadslin Frenelus, Hui Peng, Jingyu Zhang
doaj +1 more source
An analytical model of memristors in plants [PDF]
The memristor, a resistor with memory, was postulated by Chua in 1971 and the first solid-state memristor was built in 2008. Recently, we found memristors in vivo in plants. Here we propose a simple analytical model of 2 types of memristors that can be found within plants.
Markin, Vladislav S +2 more
openaire +2 more sources
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
The inclusion of an indicator of pathological prevalence is considered as an element of improvement of social and hygienic monitoring. This criterion allows considering donosological state of the human body and complexity of the development of ...
A. I. Babenko +4 more
doaj +1 more source
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
As soluções analíticas de distribuição de água para ponto fonte e regime de fluxo não- permanente são dependentes de parâmetros de solos considerados constantes em suas deduções. Erros na determinação desses parâmetros implicam insucesso dessas soluções.
Eugênio Ferreira Coêlho +2 more
doaj +1 more source

