Quality-by-design in pharmaceutical development: From current perspectives to practical applications [PDF]
, 2021 Current pharmaceutical research directions tend to follow a systematic approach in the field of applied research and development. The concept of quality-by-design (QbD) has been the focus of the current progress of pharmaceutical sciences. It is based on,
BOGLÁRKA KOVÁCS-DEÁK +6 more
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A new approach based on inversion of a partial least squares model searching for a preset analytical target profile. Application to the determination of five bisphenols by liquid chromatography with diode array detector [PDF]
, 2021 The paper shows a procedure for selecting the control method parameters (factors) to obtain a preset ‘analytical target profile’ when a liquid chromatographic technique is going to be carried out for the simultaneous determination of five bisphenols ...
Arce Antón, Mar +5 more
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Chromatographic study of sitagliptin and ertugliflozin under quality-by-design paradigm [PDF]
, 2023 The present study entails the systematic development and validation of a stability-indicating RP-HPLC method for the analysis of sitagliptin and ertugliflozin in a fixed-dose combination.
Anumolu, Panikumar Durga +4 more
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Journal of Liquid Chromatography & Related Technologies, 2017 A reversed-phase ultrafast liquid chromatography method was developed for quantification of lansoprazole in pharmaceutical dosage form using analytical quality by design approach. Systematic planning and experimentation using design of experiment approach were used for method development and optimization studies. A central composite design was used for
Panda, Sagar Suman +3 more
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International Journal of Research in Ayurveda and Pharmacy, 2023 The quantitative measurement of Glecaprevir and Pibrentasvir has been created using a simple, quick, precise, sensitive, and reproducible reverse-phase high-performance liquid chromatography (RP-HPLC) method. It is more difficult to analyse varying amounts of pharmaceutical active medicinal ingredients in dosage forms without interferences.
Nithiyananthan K, Prasada Rao KVS
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A systematic AQbD approach for optimization of the most influential experimental parameters on analysis of fish spoilage-related volatile amines [PDF]
, 2020 The volatile amines trimethylamine (TMA) and dimethylamine (DMA) could be used as important spoilage indices for seafood products, assisting in the determination of the rejection period.
Câmara, José S. +3 more
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IMPLEMENTING OF ANALYTICAL QUALITY BY DESIGN FOR HIGH QUALITY PHARMACEUTICAL PRODUCTS [PDF]
The quality in the pharmaceutical industry has become a very important topic. Pharmaceutical industry has been emerging rapidly for the last decade by focusing on product Quality, Safety, and Efficacy.
P. Abhinandana1.2*, Ramarao Nadendla2
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Selectivity study on thermochemical conversion of fruit residues (Plums) to platform chemicals (HMF) [PDF]
, 2023 5-hydroxymethylfurfural (HMF) is one of the versatile platform compounds derived from the dehydration of carbohydrates originating from biomass. However, the non-selective production of HMF from carbohydrates and its subsequent separation from the ...
Bebizuh, Dawit Firemichael
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Eco-Friendly Stability Indicating HPLC Method for Estimation of Elbasvir and Grazoprevir by Quality by Design Approach [PDF]
, 2023 Introduction: The pharmaceutical industry faces a significant problem as a result of the worldwide requirement to modify processes in order to comply with the green analytical chemistry (GAC) requirements. An enormous amount of organic hazardous waste is
Bhangale, Charushila +3 more
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Implementation of Quality by Design (QbD) approach to the analytical method development and validation for the estimation of Remogliflozin Etabonate in tablet dosage form by HPLC [PDF]
Analytical Quality by Design is a recent concept related to the development and validation of the analytical procedures (AQbD). This is done in analytical QbD by defining quality targets which enable the performance of the analytical procedure within the
Yash M. Phulwani, Shankar S. Yelmame, Laxmikant B. Borse
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