Results 101 to 110 of about 4,694,462 (306)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Journal of analytical and applied chemistry.

open access: yes, 1891
Edited by: Edward Hart.Title from cover.Contains "A bibliography of analytical chemistry ... 1866-92," by H.C.
Hart, Edward, 1854-   +1 more
core  

Analytical benchmark solutions for steel frame structures subject to local buckling effects [PDF]

open access: yes, 2000
Application of "advanced analysis" methods suitable for non-linear analysis and design of steel frame structures permits direct and accurate determination of ultimate system strengths, without resort to simplified elastic methods of analysis and semi ...
Mahendran, Mahen, Avery, Philip
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Analytical exact solutions for unsteady collisionless plume flows in a vacuum

open access: yes, 2013
This paper presents a set of gaskinetic solutions to the problem of unsteady collisionless round plume development: startup and development to a steady flow; steady flow; and shutting down from a steady flow.
Cai C   +3 more
core   +1 more source

Exploring Fractional Damped Burgers’ Equation: A Comparative Analysis of Analytical Methods

open access: yesFractal and Fractional
This investigation focuses on the study of the fractional damped Burgers’ equation by using the natural residual power series method coupled with the new iteration transform method in the context of the Caputo operator.
Azzh Saad Alshehry, Rasool Shah
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The first integral method for the perturbed Wadati-Segur- Ablowitz equation with time dependent coefficient

open access: yesKuwait Journal of Science, 2015
The first integral method (FIM) is used to construct traveling wave solutions ofperturbed Wadati-Segur-Ablowitz (pWSA) equation with time dependent coefficient inthis manuscript. We obtained some different solutions by using Gauge transformationwith time
MUSTAFA INC, BULENT KILIC
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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