Results 101 to 110 of about 3,670 (211)

Finite Element Modeling of Porous Microstructures With Random Holes of Different-Shapes and -Sizes to Predict Their Effective Elastic Behavior

Applied Sciences, 2019
Porous materials are promising media for designing medical instruments, drug carriers, and bioimplants because of their excellent biocompatibility, ease of design, and large variation of elastic moduli.
Haolin Li, Shuhao Dong, Jiantao Liu, Yaoxiang Yu, Muqing Wu, Zhengqing Zhang   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

NMR analysis of Nile Blue (C. I. Basic Blue 12) and Thionine (C. I. 52000) in solution [PDF]

, 2011
The dyes Nile Blue (C. I. Basic Blue 12, NB) and Thionine (C. I. 52000, TH) were examined in both ionic and neutral forms in different solvents using NMR and UV-visible Spectroscopy to firmly establish the structures of the molecules and to assess the ...
Evstigneev, Maxim P., Mills, Andrew, Salvia, M.V., Hutchings, Michael G., Hazafy, David, Andrew Mills, Parkinson, J., Hutchings, M.G., Salvia, Marie-Virginie, David Hazafy, Maxim P. Evstigneev, Parkinson, John A., Michael G. Hutchings, Hazafy, D., Marie-Virginie Salvia, John A. Parkinson, Mills, A., Evstigneev, M.P.   +17 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An extended two-layer viscous Boussinesq-type model for surface gravity waves: Including the effect of bottom friction

Applied Ocean Research
Wave propagation is accompanied by energy attenuation owing to the water viscosity. Based on the two-layer viscous Boussinesq-type model considering of deep-water waves, the bottom friction term is incorporated to further simulate wave energy dissipation
Hao Sun, Yang Zhao, Zhongbo Liu, Yong Liu   +3 more
doaj   +1 more source

Analytical Solution of Generalised Mandel’s Problem [PDF]

ITM Web of Conferences
Mandel’s problem considers the time-dependent deformation of a fully saturated rectangular porous material with drainage at the lateral sides and steady load from the top and bottom.
Mahdiyasa Adilan W., Justica Alma, Prastoro Tarasinta   +2 more
doaj   +1 more source

Model Development and Stability Analysis for a Turbocharger Rotor System under Multi-Field Coupled Forces [PDF]

, 2012
Automotive turbochargers have been widely applied in vehicles in order to increase the power output of internal combustion engines by increasing the air to fuel ratio entering the piston cylinders.
Zhang, Hao
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source