Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Soliton dynamics of the fourth-order nonlinear Boussinesq equation arising in shallow-water via advanced analytical techniques. [PDF]
Malik S +3 more
europepmc +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Characterising Dissolution Dynamics of Engineered Nanomaterials: Advances in Analytical Techniques and Safety-by-Design. [PDF]
Chakraborty S +2 more
europepmc +1 more source
Molecular Insights into the Interaction between CD147 and the SARS-CoV‑2 Spike Protein
Milton S. Gonzalez-Serrano +6 more
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Biodistribution of nanoplastics in mice: advancing analytical techniques using metal-doped plastics. [PDF]
Staufer T +10 more
europepmc +1 more source
Soliton solutions for the Zoomeron model applying three analytical techniques. [PDF]
Ullah MS +4 more
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Application of vibrational spectroscopies as process analytical techniques for monitoring fermentation and the conversion of lignocellulosic biomass by oleaginous filamentous fungi. [PDF]
Dzurendova S +13 more
europepmc +1 more source

