Results 161 to 170 of about 2,120,758 (270)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Molecular Insights into the Interaction between CD147 and the SARS-CoV‑2 Spike Protein

open access: yesACS Omega
Milton S. Gonzalez-Serrano   +6 more
doaj   +1 more source

Biodistribution of nanoplastics in mice: advancing analytical techniques using metal-doped plastics. [PDF]

open access: yesCommun Biol
Staufer T   +10 more
europepmc   +1 more source

Soliton solutions for the Zoomeron model applying three analytical techniques. [PDF]

open access: yesPLoS One, 2023
Ullah MS   +4 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Application of vibrational spectroscopies as process analytical techniques for monitoring fermentation and the conversion of lignocellulosic biomass by oleaginous filamentous fungi. [PDF]

open access: yesMicrob Cell Fact
Dzurendova S   +13 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Quantitative analysis of therapeutic proteins in biological fluids: recent advancement in analytical techniques. [PDF]

open access: yesDrug Deliv, 2023
Song JG   +8 more
europepmc   +1 more source

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