Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Soliton solutions of the (2 + 1)-dimensional Jaulent-Miodek evolution equation via effective analytical techniques. [PDF]
Zubair Raza M +4 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Characterization of AAV vectors: A review of analytical techniques and critical quality attributes. [PDF]
Kontogiannis T +6 more
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Analytical Techniques for Supporting Hospital Case Mix Planning Encompassing Forced Adjustments, Comparisons, and Scoring. [PDF]
Burdett RL +3 more
europepmc +1 more source
Microstructural Characterization of Dry Powder Inhaler Formulations Using Orthogonal Analytical Techniques. [PDF]
Farias G +7 more
europepmc +1 more source
Puerarin-A Promising Flavonoid: Biosynthesis, Extraction Methods, Analytical Techniques, and Biological Effects. [PDF]
Liga S, Paul C.
europepmc +1 more source
Evaluation of amylose content: Structural and functional properties, analytical techniques, and future prospects. [PDF]
Wang Y +4 more
europepmc +1 more source

