Results 31 to 40 of about 2,142,916 (291)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Ion exchange investigation for recovery of uranium from acidic pregnant leach solutions

Nukleonika, 2017
The article describes studies on the separation of uranium from acid pregnant leach solutions obtained from Polish uranium ores: dictyonema shales and sandstone rocks.
Danko Bożena, Dybczyński Rajmund S., Samczyński Zbigniew, Gajda Dorota, Herdzik-Koniecko Irena, Zakrzewska-Kołtuniewicz Grażyna, Chajduk Ewelina, Kulisa Krzysztof   +7 more
doaj   +1 more source

Mathematic Model And Error Analysis of Moving-base Rotating Accelerometer Gravity Gradiometer

, 2019
In moving-base gravity gradiometry, accelerometer mounting errors and mismatch cause a rotating accelerometer gravity gradiometer (RAGG) to besusceptible to its own motion. In this study, we comprehensively consider accelerometer mounting errors, circuit
Cai, Tijing, Yu, Mingbiao
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

A multichannel electrochemical all-solid-state wearable potentiometric sensor for real-time sweat ion monitoring

Electrochemistry Communications, 2019
There is considerable interest in wearable potentiometric ion sensors that can provide information about the quality of a person's health by monitoring ion concentration levels in biofluids.
Qingbo An, Shiyu Gan, Jianan Xu, Yu Bao, Tongshun Wu, Huijun Kong, Lijie Zhong, Yingming Ma, Zhongqian Song, Li Niu   +9 more
doaj   +1 more source

'Leave it or take it away': ethical considerations on the removal of overpainting: the case of the Ghent Altarpiece [PDF]

, 2015
During the current conservation of the Ghent Altarpiece, carried out by a team of KIK-IRPA, a large amount of old overpaint has been discovered. These are studied with a number of innovative analytical techniques.
Martens, Maximiliaan
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

The Binding of the SARS-CoV-2 Spike Protein to Platelet Factor 4: A Proposed Mechanism for the Generation of Pathogenic Antibodies

Biomolecules
Pathogenic platelet factor 4 (PF4) antibodies contributed to the abnormal coagulation profiles in COVID-19 and vaccinated patients. However, the mechanism of what triggers the body to produce these antibodies has not yet been clarified.
Thi-Huong Nguyen, Li-Yu Chen, Nida Zaman Khan, Annerose Lindenbauer, Van-Chien Bui, Peter F. Zipfel, Doris Heinrich   +6 more
doaj   +1 more source

THE USE OF ANALYTICAL PROCEDURES IN AFFILIATED AND NON-AFFILIATED AUDIT FIRMS [PDF]

, 2017
The aim of the research was to investigate the allocated time and the frequency of the use of analytical procedures in affiliated and non-affiliated audit firms, and to examine the frequency the effectiveness of various types of analytical techniques by ...
HARTO, Puji, SITI, Aisyah Fitria
core  

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source