Results 171 to 180 of about 21,890 (235)

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source

Distribution and transfer of cyclosporine among the various human lipoprotein classes [PDF]

, 1983
Graf, A., Illner, Wolf-Dieter, Land, Walter, Mraz, W., Preis, D., Siebert, W., Zink, R., Zöttlein, H.   +7 more
core   +1 more source

Conformational Equilibrium of Cysteamine on Silver Metal Surface Studied by Surface‐Enhanced Raman Scattering

Journal of Raman Spectroscopy, EarlyView.
Surface‐enhanced Raman scattering (SERS) is employed to study solvent‐induced conformational changes of cysteamine on silver bumpy nanoshells (AgNS). The trans to gauche SERS intensity ratio (Itrans/Igauche) was lowest in water and highest in aprotic acetonitrile, indicating distinct surface conformations.
Sungjun Kwak, Daeun Lee, Sung Gun Lee, Dae Hong Jeong   +3 more
wiley   +1 more source

Major Ozonated Autoheamotherapy Alleviates Skeletal Muscle Ischemia/Reperfusion Injury by Regulating Nrf2/HO‐1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Skeletal muscle ischaemia/reperfusion (I/R) injury remains a clinically significant condition characterized by muscular dystrophy. Although ozone therapy has shown protective potential against I/R injury in animal models of various organs including skeletal muscle, its precise mechanistic underpinnings require further elucidation.
Hui‐Zhuang Guo, Sheng‐Long Yu, Han‐Wei Chen   +2 more
wiley   +1 more source

Swelling Behavior and Mechanical Stability of Composite Fibers Prepared from Casein Micelles and Calcium Alginate

Macromolecular Materials and Engineering, EarlyView.
A micellar casein‐alginate blend is wet‐spun into fibers using a calcium‐rich coagulation bath. Fibers with different levels of casein are dried and tested. Swelling tests showed increased stability in decalcifying media with micellar casein. Mechanical properties remained largely unchanged, except after treatment with citric acid, where the breaking ...
Novin Darvishsefat, Ronald Gebhardt
wiley   +1 more source

Oral Delivery of Ellagic Acid Encapsulated in Milk Exosomes: Sex‐Based Differences in Bioavailability, Urolithin Production, and Gut Microbiota Modulation

Molecular Nutrition &Food Research, EarlyView.
Sex‐dependent effects on plasma metabolome and gut microbiota were observed after oral administration of ellagic acid (EA) encapsulated in milk‐derived exosomes (EXO‐EA) versus non‐encapsulated EA (NEA) and non‐loaded EXOs. EXO‐EA impacted plasma metabolome, modulated gut microbiota, and increased urolithin A and SCFA production sex‐dependently ...
María Ángeles Ávila‐Gálvez, María Romo‐Vaquero, Carmen Mazarío‐Gárgoles, Joao Tomé‐Carneiro, María‐Carmen López de las Hazas, Alberto Dávalos, María Victoria Selma, Antonio González‐Sarrías, Juan Carlos Espín   +8 more
wiley   +1 more source

Microfluidic Systems in Cancer Diagnosis: Advancing Exosome and CTC Detection From Laboratory Research to Clinical Application

Nano Select, EarlyView.
Detection of cancer through the identification of EV markers and CTCs using microfluidic systems is rapidly advancing. These markers are typically identified from liquid biopsy samples, which offer a highly favorable alternative to traditional biopsy methods due to their non‐invasive nature.
Bahareh Valinezhad Saghezi, Kamran Mansouri, Rahman Hallaj   +2 more
wiley   +1 more source

Establishment of a Protocol for CE‐MS Based Peptidome Analysis of Human Saliva

PROTEOMICS, EarlyView.
ABSTRACT Proteins and peptides indicate physiological or pathological states and are investigated to identify markers to scrutinize health and disease surveillance. Saliva contains many proteins and peptides that could serve as biomarkers, offering a potential noninvasive approach for disease detection.
Carl‐Johan Törnhage, Björn Peters, Agnieszka Latosinska, Ioanna K. Mina, Marika Mokou, Harald Mischak, Justyna Siwy   +6 more
wiley   +1 more source

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, EarlyView.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source