Results 91 to 100 of about 1,278,043 (329)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Enhancing Accessibility to Analytics Courses in Higher Education through AI, Simulation, and e-Collaborative Tools

open access: yesInformation
This paper explores how the combination of artificial intelligence, simulation, and e-collaborative (AISEC) tools can support accessibility in analytics courses within higher education.
Celia Osorio   +4 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The impact of big data analytics on digital marketing decision-making: A comprehensive analysis [PDF]

open access: yesInnovative Marketing
Type of the article: Research Article AbstractThe fast development of data availability has altered digital marketing, establishing big data analytics as a vital tool for optimizing decision-making and enhancing campaign performance. This study explores
Roberta Bajrami   +3 more
doaj   +1 more source

Exploring Application Performance on Emerging Hybrid-Memory Supercomputers

open access: yes, 2017
Next-generation supercomputers will feature more hierarchical and heterogeneous memory systems with different memory technologies working side-by-side.
Gioiosa, Roberto   +4 more
core   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Editorial: Analytics and Mathematics in Adaptive and Smart Learning

open access: yesFrontiers in Applied Mathematics and Statistics, 2022
Shriram Raghunathan   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Method of Situation Analysis of International Relations as A Forecasting Tool Under Conditions of Transforming World Order

open access: yesVestnik MGIMO-Universiteta, 2019
The article discusses the method of situation analysis of international relations, developed in the 1960s in the Primakov National Research Institute of World Economy and International Relations by Academician Evgeniy Primakov.
V. G. Baranovsky   +3 more
doaj   +1 more source

Damned Lies & Criminal Sentencing Using Evidence-Based Tools [PDF]

open access: yes, 2017
The boom of big data and predictive analytics has revolutionized business. eHarmony matches customers based on shared likes and expectations for romance, and Target uses similar methods to strategically push its products on shoppers.
Lightbourne, John
core   +1 more source

Home - About - Disclaimer - Privacy