Results 101 to 110 of about 3,624,229 (370)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Big Data in Designing Clinical Trials: Opportunities and Challenges

open access: yesFrontiers in Oncology, 2017
Emergence of big data analytics resource systems (BDARSs) as a part of routine practice in Radiation Oncology is on the horizon. Gradually, individual researchers, vendors, and professional societies are leading initiatives to create and demonstrate use ...
Charles S. Mayo   +5 more
doaj   +1 more source

Data Challenges in High-Performance Risk Analytics

open access: yes, 2013
Risk Analytics is important to quantify, manage and analyse risks from the manufacturing to the financial setting. In this paper, the data challenges in the three stages of the high-performance risk analytics pipeline, namely risk modelling, portfolio ...
Rau-Chaplin, Andrew, Varghese, Blesson
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Correspondence and Analyticity

open access: yesPublications of the Research Institute for Mathematical Sciences, 2004
The analyticity properties of the S-matrix in the physical region are determined by the correspondence principle, which asserts that the predictions of classical physics are generated by taking the classical limit of the predictions of quantum theory.
openaire   +5 more sources

Immersive analytics

open access: yesIEEE Computer Graphics and Applications, 2019
Welcome and Overview Visualisation and Visual Analytics Introduction to Immersive Analytics Computing Beyond the Desktop ...
T. Chandler   +10 more
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Library impact data: investigating library use and student attainment [PDF]

open access: yes, 2015
Analytics are increasingly being used to uncover new narratives and demonstrate new types of value and impact for libraries and their institutions. This section will explore some of the current opportunities that institutions are exploiting with the use ...
Stone, Graham
core  

Internet of Things and Big Data Analytics for Smart and Connected Communities

open access: yesIEEE Access, 2016
This paper promotes the concept of smart and connected communities SCC, which is evolving from the concept of smart cities. SCC are envisioned to address synergistically the needs of remembering the past (preservation and revitalization), the needs of ...
Yunchuan Sun   +3 more
semanticscholar   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

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