Results 101 to 110 of about 2,985,531 (342)

Big data analytics in E-commerce: a systematic review and agenda for future research

open access: yesElectronic Markets, 2016
There has been an increasing emphasis on big data analytics (BDA) in e-commerce in recent years. However, it remains poorly-explored as a concept, which obstructs its theoretical and practical development.
Shahriar Akter, S. Wamba
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Quaternionic analyticity

open access: yesApplied Mathematics Letters, 2003
n ...
S. DE LEO, ROTELLI, Pietro
openaire   +3 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

On Analytic Theology

open access: yesScientia et Fides, 2015
My primary aims in this paper are to give an overview of a recent movement which goes by the name of ‘analytic theology’, to locate that movement within the larger context of contemporary philosophy of religion, and to identify some of the weakness or objections that analytic theology will need to address moving forward. While I think
Timpe, K. (Kevin), Timpe, K. (Kevin)
openaire   +5 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

THE FLUCTUATIONS OF MULTI-TIERED AND MULTI-SPAN REGULAR FRAMES

open access: yesNauka ta progres transportu, 2009
Exact analytical decisions are presented for free flexing vibrations of multiple-deck and multiple-bay regular frames taking into account inertia of rotation, shifts, and static longitudinal forces.
O. S. Raspopov   +2 more
doaj  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Analytical Sciences

open access: yesCHIMIA, 2010
The research group for analytical and bioanalytical sciences at the Department of Chemistry of the University of Basel is working on miniaturization of analytical techniques, with special focus on detection. Downsizing is a challenge for quantitation and contributions have been made based on different techniques which encompass atomic and ...
openaire   +6 more sources

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