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Big Data Analytics in Medicine and Healthcare
This paper surveys big data with highlighting the big data analytics in medicine and healthcare. Big data characteristics: value, volume, velocity, variety, veracity and variability are described.
B. Ristevski, Ming Chen
semanticscholar +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
Reactions of sugars and polyatomic alcohols in boric acid and borate solutions, with some analytical applications [PDF]
G. Van B. Gilmour
openalex +1 more source
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
Analytically heavy spaces: Analytic Cantor and Analytic Baire Theorems
AbstractMotivated by recent work, we establish the Baire Theorem in the broad context afforded by weak forms of completeness implied by analyticity and K-analyticity, thereby adding to the ‘Baire space recognition literature’ (cf. Aarts and Lutzer (1974) [1], Haworth and McCoy (1977) [43]).
openaire +2 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Analytic cycles on real analytic manifolds
Let X be a compact real analytic manifold of dimension n. In this paper we study homology classes in H∗(X,Z/2) represented by analytic subsets of X. Here a subset V of X is called analytic if V = f(0), where f : X → R is an analytic function. Thus analytic sets are zeros of global analytic functions.
J. Bochnak+2 more
openaire +4 more sources
Spiral and Other Asymptotic Paths, and Paths of Complete Indetermination, of Analytic and Meromorphic Functions [PDF]
F. Bagemihl, W. Seidel
openalex +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source