Results 121 to 130 of about 3,666,634 (374)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Analytics Team Claims Second Place in National Analytics Challenge [PDF]

open access: yes, 2018
Business students take home national award in Association for Information Systems national analytics ...
Rodrigues, Jill
core   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Enhancing Accessibility to Analytics Courses in Higher Education through AI, Simulation, and e-Collaborative Tools

open access: yesInformation
This paper explores how the combination of artificial intelligence, simulation, and e-collaborative (AISEC) tools can support accessibility in analytics courses within higher education.
Celia Osorio   +4 more
doaj   +1 more source

Situated Analytics [PDF]

open access: yes, 2018
This chapter introduces the concept of situated analytics that employs data representations organized in relation to germane objects, places, and persons for the purpose of understanding, sense making, and decision-making. The components of situated analytics are characterized in greater detail, including the users, tasks, data, representations ...
Thomas, Bruce   +10 more
openaire   +3 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

The Method of Situation Analysis of International Relations as A Forecasting Tool Under Conditions of Transforming World Order

open access: yesVestnik MGIMO-Universiteta, 2019
The article discusses the method of situation analysis of international relations, developed in the 1960s in the Primakov National Research Institute of World Economy and International Relations by Academician Evgeniy Primakov.
V. G. Baranovsky   +3 more
doaj   +1 more source

Analytical chemistry [PDF]

open access: yesAnnual Reports on the Progress of Chemistry, 1911
n ...
openaire   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Editorial: Analytics and Mathematics in Adaptive and Smart Learning

open access: yesFrontiers in Applied Mathematics and Statistics, 2022
Shriram Raghunathan   +2 more
doaj   +1 more source

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