Results 141 to 150 of about 1,307,632 (280)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Purpose: The article presents the development of a framework to analyze the use of big data and analytics in organizations. The framework is based on affordance theory and actor-network theory (ANT).
Luisa M. Strauss, Norberto Hoppen
doaj
Multi‐Parametric Decision System for Analytical Performance Assessment of Electrochemical (Bio)Sensors [PDF]
Daniel C. Moreira +5 more
openalex +1 more source
A NOVEL ANALYTICAL MODEL OF POWER SPECTRAL DENSITY FUNCTION COHERENT WITH EARTHQUAKE RESPONSE SPECTRA [PDF]
Giorgio Barone +3 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Analyticity of quantum states in one-dimensional tight-binding model [PDF]
Hiroaki S. Yamada, Kensuke S. Ikeda
openalex +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Hybrid analytical method for calibrating a standard NaI(Tl) gamma-ray scintillation detector using a lateral hexagonal radioactive source [PDF]
Mohamed S. Badawi +2 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

