Results 161 to 170 of about 1,307,632 (280)

Methods of assessing of tax incentives effectiveness in special economic zones: An analytical overview [PDF]

, 2016
Olga Sinenko
openalex   +1 more source

Connecticut Light and Power C&LM Programs/Residential Load Management Services Program: 2002 Summer and Winter Thermostat Pilot Programs Impact Evaluation Report [PDF]

, 2003
RLW Analytics, Inc.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Ethical challenges and opportunities for integrating predictive analytics in community-based overdose prevention. [PDF]

Lancet Reg Health Am
Allen B, Urmanche A, Curtis B, Fisher C.
europepmc   +1 more source

A numerical-analytical approach to determining the real contact area of rough surface contact [PDF]

, 2020
Can Wang, Dik J. Schipper
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Evaluating digital maturity in public health systems: a statewide cross-sectional analysis of digital public health capacity in Missouri. [PDF]

Front Public Health
Snowdon A, Wright A, Hussein A, Wymer J, Howgate J, Storey T.   +5 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Data Analytics and Administrative Decision-Making in Nursing Management: A Systematic Review. [PDF]

J Nurs Manag
Darach N, Kim MS, Wisesrith W, Collins EG.   +3 more
europepmc   +1 more source

Clinical and analytical monitoring of patients with multiple sclerosis on anti-CD20 therapeutics: a real-world safety profile study [PDF]

André Aires Fernandes, Ana Lídia Neves, Daniela Ferro, Mafalda Seabra, Teresa Mendonça, Ricardo Soares-dos-Reis, María José Sá, Joana Guimarães, Pedro Abreu   +8 more
openalex   +1 more source