On the convergence and overconvergence of sequences of polynomials of best simultaneous approximation to several functions analytic in distinct regions [PDF]
, 1934 J. L. Walsh, Helen G. Russell
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Correction: Global, regional, and national epilepsy of unknown cause incidence and mortality, 1990-2036: cross-national health inequalities and predictive analytics. [PDF]
Front NeurolWang Y, Wang Y, Qiu X, Yu Z, Wang L.
europepmc +1 more source
Spiral and Other Asymptotic Paths, and Paths of Complete Indetermination, of Analytic and Meromorphic Functions [PDF]
, 1953 F. Bagemihl, W. Seidel
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Editorial: Navigating the nexus of big data, AI, and public health: transformations, triumphs, and trials in multiple sclerosis care access. [PDF]
Front Big DataMoonesar IA +4 more
europepmc +1 more source