Results 241 to 250 of about 669,987 (295)

America First, Africa Last? Health data deals and the new scramble for pathogens. [PDF]

PLOS Glob Public Health
Sekalala S, Lake SJ, Maleche A, Wafula T.   +3 more
europepmc   +1 more source

Derived products and analytical scripts for "Seasonal to decadal dynamics of supraglacial lakes on debris-covered glaciers in the Khumbu Region, Nepal"

Lucas Zeller, Daniel McGrath, Scott McCoy, Jonathan Jacquet   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Building a healthcare data warehouse: considerations, opportunities, and challenges. [PDF]

Front Digit Health
Knezevic Ivanovski T, Honap S, Matic R, Markovic S, Peyrin-Biroulet L.   +4 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Leveraging artificial intelligence community analytics and nanopore metagenomic surveillance to monitor early enteropathogen outbreaks. [PDF]

Front Public Health
Gauthier J, Mohammadi S, Kukavica-Ibrulj I, Boyle B, Landgraff C, Goodridge L, White K, Chapman B, Levesque RC.   +8 more
europepmc   +1 more source

A platform for generating clinical intelligence from routine health data in hospitals: PICTURE. [PDF]

Future Healthc J
Bowyer SA, Pissaridou E, Booth J, Key D, Bryant WA, Sheldon E, Zenonos A, Pope R, Hemingway H, Taylor A, Sebire NJ.   +10 more
europepmc   +1 more source

Creativity in Learning Analytics: A Systematic Literature Review. [PDF]

J Intell
Mirzaei S, Nikmehr H, Liu S, Marmolejo-Ramos F.   +3 more
europepmc   +1 more source