Results 71 to 80 of about 25,306 (190)

Tumor‐type–specific expression of TTF‐1 in primary central nervous system tumors classified by the 2021 WHO criteria

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Thyroid transcription factor‐1 (TTF‐1) is a widely used immunohistochemical marker for tumors of thyroid and pulmonary origin; however, its expression profile and diagnostic relevance in primary central nervous system (CNS) tumors remain incompletely characterized, particularly following the revisions in the 2021 WHO Classification of CNS ...
Lu Xu, Hong‐Jiu Ren, Jian Gu, Bing‐Wen Shan, Tong Ren, Chu‐Hang Liu, Chun‐Xian Cai, Xiao‐Yu Zhang, Juan‐Han Yu   +8 more
wiley   +1 more source

Anaplastic Ependymoma With Ganglionic Differentiation: Report of a Rare Case and Implications in Diagnosis

, 2017
Ependymomas are glial neoplasms with rare cases exhibiting neuronal differentiation. We describe a case of spinal anaplastic ependymoma with ganglionic differentiation in a 28-year-old woman.
Niveditha Ravindra, Bhagavatula Indira Devi, Nishanth Sadashiva, Shilpa Rao, Vani Santosh   +4 more
core   +1 more source

Limitations of current in vitro models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymoma [PDF]

, 2018
Background: Epigenetic modifications have been shown to play an important role in the classification and pathogenesis of the pediatric brain tumor ependymoma, suggesting they are a potential therapeutic target.Results: Agents targeting epigenetic ...
Barron-Hastings, Jodie, Pajtler, Kristian W., Rogers, Hazel Anne, Grundy, Richard Guy, Sill, Martin, Chapman, Rebecca, Pfister, Stefan, Allard, Julie, Kings, Holly   +8 more
core   +1 more source

A 67‐year‐old man with a spinal extramedullary mass

Brain Pathology, EarlyView.
Marcella Callea, Francesco Costa, Rosina Paterra, Valeria Barresi   +3 more
wiley   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

Treatment of patients with anaplastic ependymoma under three years of age

, 2018
Çocukluk çağı ependimomlarının yaklaşık üçte ikisi posterior fossa yerleşimli olup daha az bir kısmı supratentorial veya spinal intramedüller yerleşimlidir.
Serhan Küpeli, Begül Küpeli Yağcı
core   +2 more sources

Pediatric infratentorial ependymoma: prognostic significance of anaplastic histology

, 2011
Pediatric infratentorial ependymomas are difficult to cure. Despite the availability of advanced therapeutic modalities for brain tumors, total surgical resection remains the most important prognostic factor.
Lee, Ji Yeoun, Ji Hoon Phi, Son, Young-Je, In-One Kim, Wang, Kyu-Chang, Park, Sung-Hye, Sung-Hye Park, Park, Kyung Duk, Ji Yeoun Lee, Kim, Il Han, Ahn, Hyo Seop, Kyung Duk Park, Phi, Ji Hoon, Seung-Ki Kim, Kim, In-One, Hyo Seop Ahn, Kyu-Chang Wang, Young-Je Son, 박성혜, Kim, Seung-Ki, Il Han Kim   +20 more
core   +1 more source

Early‐Onset Medullocervical Low‐Grade Glioma With FGFR1 Mutation and Leptomeningeal Spread in an Infant: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pediatric low‐grade gliomas (PLGGs) are generally slow‐growing tumors associated with favorable long‐term outcomes. However, their occurrence in early infancy is rare, particularly when arising in the posterior fossa with extensive dissemination and hydrocephalus.
Thaer A. Tumar, Mahdi W. Suboh, Mones H. Atatre, Hanin Shatrit, Qais M. Alnjoom   +4 more
wiley   +1 more source

Extra-axial giant falcine ependymoma with ultra-rapid growth in child: Uncommon entity with literature review

Journal of Pediatric Neurosciences, 2016
Ependymoma tends to occur commonly along either on ventricular surfaces of the brain or central canal of the spinal cord. Rarely, ependymoma can develop in the cerebral cortex without attachment to the ventricular structures.
Guru Dutta Satyarthee, Luis Rafael Moscote-Salazar   +1 more
doaj   +1 more source

Pediatric spinal ependymomas: Long‐term surgical outcomes in a cohort of 61 cases

Pediatric Investigation, Volume 10, Issue 3, Page 240-248, June 2026.
Spinal ependymomas are rare in children, with limited long‐term outcome data. In this retrospective study of 61 pediatric patients undergoing surgical resection, gross total resection was achieved in 62.3% and was associated with favorable functional improvement. Recurrence was observed in 31.1% of cases.
Liang Zhang, Xingyu Liu, Bo Han, Wenqing Jia   +3 more
wiley   +1 more source