Results 101 to 110 of about 254,472 (338)
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos +14 more
wiley +1 more source
Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT A molecular diagnosis is currently achievable in approximately 50% of patients assessed by clinical geneticists at tertiary care centres. Next‐Generation Sequencing Panels contain a defined group of genes associated with a clinically defined set of phenotypes.
Ana Acosta Bedón +10 more
wiley +1 more source
Конденсированные среды и межфазные границы, 2017 The granulation of titanium magnetite concentrate containing up to Fe – mass fraction 54 %, TiO2 – 7 %, V – and 1 % Mn – 0.8 %, with 25 % mass fraction fl uxing additives soda has been modelled.
Mamedov Asif Nasib ogly +3 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source
The medIeval Dashbulag settlement
Поволжская археологияThe article deals with the archaeological excavation of the Dashbulag settlement located in Shamkir district in the west of Azerbaijan. The step-by-step progress of the archaeological excavations conducted in the medieval settlement of Dashbulag, the ...
Najafov Shamil N. +2 more
doaj +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton +217 more
wiley +1 more source
IgG, IgM, and IgA Antinuclear Antibodies in Discoid and Systemic Lupus Erythematosus Patients
The Scientific World Journal, 2014 IgG antinuclear antibodies (ANAs) are elevated in patients with systemic lupus erythematosus (SLE) compared with patients with discoid lupus erythematosus (DLE).
Sheridan A. Jost +6 more
doaj +1 more source
Map++: A Crowd-sensing System for Automatic Map Semantics Identification
, 2015 Digital maps have become a part of our daily life with a number of commercial and free map services. These services have still a huge potential for enhancement with rich semantic information to support a large class of mapping applications. In this paper,
Aly, Heba +2 more
core +1 more source
Challenges of modeling pristane‐induced lupus in non‐human primates
Animal Models and Experimental Medicine, EarlyView.Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova +5 more
wiley +1 more source
Brain Atrophy Associated With Risk Variant rs10191329 Extends Beyond Multiple Sclerosis
Annals of Neurology, EarlyView.The risk allele rs10191329*A is associated with disease severity and brain atrophy in people with multiple sclerosis (MS). We investigated the association of rs10191329 with age‐related brain atrophy in a population‐based cohort using 10,308 magnetic resonance imaging (MRI) scans of 4,815 participants aged ≥ 45 years without MS in cross‐sectional and ...
Cato E. A. Corsten +10 more
wiley +1 more source