Results 161 to 170 of about 73,090 (309)

Neoadjuvant Atezolizumab and Chemotherapy for Non‐Squamous Non‐Small Cell Lung Cancer: Efficacy and Safety Results of an Open‐Label, Single‐Arm, Phase II Trial

International Journal of Cancer, EarlyView.
Surgery plus chemotherapy is a well‐established treatment protocol for resectable, locally advanced non‐small cell lung cancer (NSCLC). Nonetheless, survival gains remain limited, emphasizing the need for more effective treatments. Here, the authors evaluated a novel approach using a neoadjuvant immunotherapy‐chemotherapy regimen consisting of ...
Benedikt Niedermaier, Tilmann Bochtler, Florian Eichhorn, Raffaella Griffo, Laura V. Klotz, Michael Allgäuer, Albrecht Stenzinger, Helge Bischoff, Marc A. Schneider, Petros Christopoulos, Uwe Haberkorn, Claus Peter Heussel, Inka Zoernig, Felix J. F. Herth, Michael Thomas, Alexander Rölle, Hauke Winter, Axel Benner, Dirk Jaeger, Martin E. Eichhorn   +19 more
wiley   +1 more source

Effects of ghrelin on colonic anastomosis following radiotherapy

, 2016
Background: Ghrelin has been reported to have properties such as inducing proliferation, migration and angiogenesis of vascular endothelial cells and has anti-inflammatory effects which may help wound healing in anastomosis following neoadjuvant ...

core  

Total Neoadjuvant Treatment for Esophageal Adenocarcinoma With Oligometastases: TNT‐OES‐1 Trial

International Journal of Cancer, EarlyView.
Total neoadjuvant therapy could combine the potentially strong systemic effect of FLOT chemotherapy with the good locoregional control of CROSS chemoradiotherapy. While total neoadjuvant therapy is increasingly used in rectal cancer, its potential in gastroesophageal cancer remains largely unexplored.
Charlène J. van der Zijden, Tamara J. Huizer, Ben M. Eyck, Ate van der Gaast, Leni van Doorn, Marjolein Y. V. Homs, J. Jan B. van Lanschot, Joost J. M. E. Nuyttens, Lindsey Oudijk, Manon C. W. Spaander, Bas P. L. Wijnhoven, Bianca Mostert, Sjoerd M. Lagarde   +12 more
wiley   +1 more source

Intertwin birth weight discordance, mode of delivery, and fetal and neonatal outcomes in twin pregnancies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The aim of the present study was to evaluate the association between intertwin birth weight discordance and fetal and neonatal outcomes in twin pregnancies, and to assess its relationship with mode of delivery. Methods This retrospective cohort study included twin pregnancies delivered at a tertiary referral center.
Ana Martínez‐Zarco, Javier Sánchez‐Romero, José Eliseo Blanco‐Carnero, Paz Crespo‐Bañón, Romina Sol Liandro, Miriam Pertegal‐Ruiz, Walter Plasencia‐Acevedo, Aníbal Nieto‐Díaz, Catalina de Paco‐Matallana   +8 more
wiley   +1 more source

Normothermic Machine Perfusion vs. Static Cold Storage for DBD Liver Transplantation in High‐MELD Recipients: A Single‐Center Retrospective Study

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Purpose While normothermic machine perfusion (NMP) has benefits over static cold storage (SCS), its efficacy in high‐acuity recipients with high Model for End‐Stage Liver Disease (MELD) scores, particularly using a back‐to‐base application model, is not well established.
Yuzuru Sambommatsu, Daisuke Imai, Kush Savsani, Mallika Datta, Junpei Tarashi, Jacob Hallesy, Samuel Wolfe, Isao Yokota, Seung Duk Lee, David A. Bruno   +9 more
wiley   +1 more source

Effect of Human Amniotic Membrane on Prevention of Colorectal Anastomosis Leakage in Cases with Neoadjuvant Radiotherapy: An Experimental Animal Study

Iranian Journal of Medical Sciences, 2016
Background: Radiotherapy is one of the most important factors which results in negative effects on wound healing and increases anastomosis leakage. Diverting loop ileostomy has been usually performed after colorectal anastomosis in cases of colorectal ...
Sam Moslemi, Sajjad Ahmadi Joraghi, Reza Roshanravan, Leila Ghahramani, Mohammad Mohammadianpanah, Masood Hosseinzadeh, Abbas Rezaianzadeh, Ahmed Mohammed Ali Hussein, Neda Najibpour, Seyed Vahid Hosseini   +9 more
doaj  

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba, Carlos Walter Sobrado, Elizete Aparecida Lomazi, Mariana Deboni, Michela Cynthia da Rocha Marmo, Vanessa Adriana Scheeffer, Silvio da Rocha Carvalho, Adérson Omar Mourão Cintra Damião, Matheus Freitas Cardoso de Azevedo, Carlos Frederico Sparapan Marques, Eytan Wine, Artur Figueiredo Delgado, Clovis Artur Almeida da Silva Full   +12 more
wiley   +1 more source

Genetic Structure of Populations of <i>Rhizoctonia solani</i> Anastomosis Group (AG)-2-2IIIB and AG-4HGI Causing Sugar Beet Root Diseases in China. [PDF]

J Fungi (Basel)
Zhao C, Yan Z, Li P, Han C, Yang A, Wu X.   +5 more
europepmc   +1 more source

Outcomes and adverse effects of teduglutide treatment with periodic withdrawal in pediatric short bowel patients

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives We evaluated the efficacy and safety of teduglutide in a real‐world cohort in which national reimbursement policies required treatment interruptions. The primary outcomes were reduction in parenteral support (PS) and treatment‐related adverse effects, and the secondary outcome was the impact of the mandated withdrawal periods ...
Riikka Gunnar, Annika Mutanen, Mikko P. Pakarinen, Laura Merras‐Salmio   +3 more
wiley   +1 more source

Anastomotic leak after manual circular stapled left-sided bowel surgery: analysis of technology-, disease-, and patient-related factors.

Anastomotic leak rates after colorectal surgery remain high. In most left-sided colon and rectal resection surgeries, a circular stapler is utilized to create the primary bowel anastomosis.
European Society of Coloproctology (ESCP) Circular Stapled Anastomosis Working Group and 2017 European Society of Coloproctology (ESCP) Collaborating Group
core   +1 more source