Results 41 to 50 of about 246,492 (296)

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Monitoring perioperative serum albumin can identify anastomotic leakage in colorectal cancer patients with curative intent

Asian Journal of Surgery, 2018
Background: Preoperative hypoalbuminemia is a well-known risk factor for anastomotic leakage after colorectal surgery, but the association between perioperative albumin level and anastomotic leakage has not been fully investigated in curative colorectal ...
Tadanobu Shimura, Yuji Toiyama, Junichiro Hiro, Hiroki Imaoka, Hiroyuki Fujikawa, Minako Kobayashi, Masaki Ohi, Yasuhiro Inoue, Yasuhiko Mohri, Masato Kusunoki   +9 more
doaj   +1 more source

The Role of Indocyanine Near-Infrared Fluorescence in Colorectal Surgery

Frontiers in Surgery, 2022
PurposesThe aim of this study was to evaluate the importance of Indocyanine Green in control of anastomosis perfusion and on anastomotic leakage rates during laparoscopic and robotic colorectal procedures.MethodsA retrospective review of patients who ...
Francesco Maione, Michele Manigrasso, Alessia Chini, Sara Vertaldi, Pietro Anoldo, Anna D’Amore, Alessandra Marello, Carmen Sorrentino, Grazia Cantore, Rosa Maione, Nicola Gennarelli, Salvatore D’Angelo, Nicola D’Alesio, Giuseppe De Simone, Giuseppe Servillo, Marco Milone, Giovanni Domenico De Palma   +16 more
doaj   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Suspension and suturing technique can reduce the incidence of anastomotic leakage after rectal cancer excision: a single, prospective, cohort study

Scientific Reports
To evaluate the value of suspension and suturing technique in the prevention of anastomotic leakage of rectal cancer following double stapling technique.
Wei Ge, Li-hua Shao, Gang Chen, Yu-dong Qiu   +3 more
doaj   +1 more source

Anastomotic leakage and postoperative mortality in patients after esophageal cancer resection

Journal of International Medical Research, 2021
Objective Esophagectomy is a high-risk surgical procedure with significant postoperative morbidity and mortality. This study aimed to investigate the risk factors of cervical anastomotic leakage and postoperative mortality. Methods In this retrospective,
Quanguan Su, Chenxi Yin, Wei Liao, Haoxian Yang, Liying Ouyang, Rong Yang, Gang Ma   +6 more
doaj   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

Advanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu, Yiyin Rong, Bai Sun, Ziwen Sun, Yifan Wang, Xiaobin Ren, Zelin Cao, Kaikai Gao, Jiawei Yu, Zhenkun Wang, Haoxuan Ma, Jichun Guo, Kai Cao, Mengrun Kang, Songling Wang, Fenggang Ren, Yi Lv, Qiang Lu   +17 more
wiley   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

BJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro, J. H. Kauppila, S. Markar, A. Johar, P. Lagergren   +4 more
wiley   +1 more source

Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections

Gastroenterology Research and Practice, 2016
Background. The rate of anastomotic leakage is high in surgeries for Crohn’s disease, and therefore a temporary diverting stoma is often needed. We conducted this study to investigate whether preoperative nutritional therapy could reduce the risk of ...
Zhen Guo, Dong Guo, Jianfeng Gong, Weiming Zhu, Lugen Zuo, Jing Sun, Ning Li, Jieshou Li   +7 more
doaj   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source