Results 61 to 70 of about 129,452 (301)

Epidemiological associations between brachycephaly and upper respiratory tract disorders in dogs attending veterinary practices in England [PDF]

, 2015
Background: Brachycephalic dog breeds are increasingly common. Canine brachycephaly has been associated with upper respiratory tract (URT) disorders but reliable prevalence data remain lacking.
AG Drake, AJ German, AK Hussein, Anon, BR Kirkwood, C Rusbridge, CD Knecht, CV Torrez, D Alderton, D Aron, D Bannasch, D Georgevsky, D Lorenzi De, DA Koch, DG O’Neill, DG O’Neill, DG O’Neill, DN Irion, EM Lund, F Bernaerts, FJ Fasanella, FS Roedler, HG Parker, I Dohoo, J Clutton-Brock, J Sampson, JJ Schoenebeck, JJ Schoenebeck, K Lindblad-Toh, L Asher, LM Collins, MJ Schmidt, MW Neff, NJ Beausoleil, P Bateson, PD McGreevy, RMA Packer, S Fonfara, S Isono, T Emmerson   +39 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Toe flexion movement with tendon excursion based on anatomical variation: A cadaver study

Journal of Orthopaedics, Trauma and Rehabilitation, 2022
Background/Purpose To investigate the relationship between anatomical variation of the toe flexor muscles and the resulting variation of toe flexion angle from tendon excursion.
Kento Hirota, Kota Watanabe, Yuki Saito, Hiroki Miyamoto, Keisuke Negishi, Atsushi Teramoto, Masaki Katayose   +6 more
doaj   +1 more source

Fully automated segmentation and tracking of the intima media thickness in ultrasound video sequences of the common carotid artery [PDF]

, 2013
—The robust identification and measurement of the intima media thickness (IMT) has a high clinical relevance because it represents one of the most precise predictors used in the assessment of potential future cardiovascular events.
A. Stanton, Alice Stanton, Alice Stanton, Alice Stanton, Alice Stanton, C. Duffy, Caoimhe Duffy, Caoimhe Duffy, Caoimhe Duffy, Caoimhe Duffy, D. E. Ilea, Dana E. Ilea, Dana E. Ilea, Dana E. Ilea, Dana E. Ilea, L. Kavanagh, Liam Kavanagh, Liam Kavanagh, Liam Kavanagh, Liam Kavanagh, P. F. Whelan, Paul F. Whelan, Paul F. Whelan, Paul F. Whelan, Paul F. Whelan   +24 more
core   +2 more sources

Anatomical variations in the digastric muscle [PDF]

The Kaohsiung Journal of Medical Sciences, 2019
The aim of this study was to investigate anatomical variations in the digastric muscle. Anatomical dissections of the head and neck region were performed in 15 cadavers at the Anatomy Department during a gross anatomy course. Three cadaver heads revealed anatomical variations in the anterior belly of the digastric muscle.
Hsiao, Tin‐Hsin, Chang, Hong‐Po
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Rare Anatomical Variation in Branching Pattern of Ulnar Nerve [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: Recognition of peripheral nerve variations plays a crucial role in therapist or surgeon evaluations. In human arm, ulnar nerve is one of the three principal nerves that move from the neck down to the hand and provide sense and ...
Alborz Jafaei Soogh, Forouzan Absalan, Firoozeh Niazvand   +2 more
doaj  

Occurrence and Regional Distribution of TRAIL and DR5 on Temporomandibular Joint Discs: Comparison of Disc Derangement with and without Reduction [PDF]

, 2010
Background Tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) is an apoptosis-inducing member of the TNF gene family which triggers apoptotic signals by interaction with its receptors.
Almeida, Luis Eduardo, Leonardi, Rosalia, Loreto, Carla, Trevilatto, Paula C.   +3 more
core   +1 more source

MTN-001: Randomized Pharmacokinetic Cross-Over Study Comparing Tenofovir Vaginal Gel and Oral Tablets in Vaginal Tissue and Other Compartments [PDF]

, 2013
Background: Oral and vaginal preparations of tenofovir as pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection have demonstrated variable efficacy in men and women prompting assessment of variation in drug concentration as an ...
A Pruvost, Alexandra M. Minnis, AS Mohamed, Barbra A. Richardson, Beatrice A. Chen, BL Robbins, BL Robbins, BP Kearney, C Mitchell, CD Blaskewicz, Clemensia Nakabiito, Craig Hoesley, Craig W. Hendrix, Gilda Tachedjian, J Balzarini, J Nuttall, JB Dumond, Jessica Justman, JL Schwartz, JW Reagan, JW Reagan, Kailazarid Gomez, Karen Patterson, KB Patterson, L Belec, Lydia Soto-Torres, M Simiele, MJ Keller, Namandje N. Bumpus, P Barditch-Crovo, PL Anderson, Q Abdool Karim, RM Grant, Robert Salata, Sharavi Gandham, SS Karim, T King, V Naranbhai, Vijayanand Guddera, WY Gao   +39 more
core   +5 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source