Results 61 to 70 of about 219,202 (303)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Radial Variation of Wood Anatomical Properties Determines the Demarcation of Juvenile-Mature Wood in Schima superba

open access: yes, 2021
Schima superba is a precious broadleaf tree species that produces excellent timber. Analyzing the radial variation of wood anatomical properties within stems and determining the boundary between the juvenile and mature wood can provide a theoretical ...
Rui Zhang, Zhichun Zhou, Yunpeng Wang
core   +1 more source

Clinically significant anatomical variation of the retropharyngeal internal carotid arteries

open access: yesRadiology Case Reports, 2017
Although interpatient variations in the course and anatomy of extracranial internal carotid arteries (EICAs) have been described previously, intrapatient variability is rarely cited in the literature.
Jaskirat K. Gill, MD   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Discrepancies in Knee Joint Moments Using Common Anatomical Frames Defined by Different Palpable Landmarks [PDF]

open access: yes, 2008
The aim was to investigate the effects of three anatomical frames using palpable anatomical landmarks of the knee on the net knee joint moments. The femoral epicondyles, femoral condyles, and tibial ridges were used to define the different anatomical ...
Jim Richards   +5 more
core   +1 more source

Vascular anatomical variation in laparoscopic right hemicolectomy

open access: yesAsian Journal of Surgery, 2020
Summary: Laparoscopic complete mesocolic excision is gradually becoming the standard surgical approach in colon cancer therapy, the core element of which is central vascular ligation.
Ke-Kang Sun, Hua Zhao
doaj   +1 more source

Anatomical variations of the hand extensors

open access: yesFolia Morphologica, 2013
This study was performed to investigate the anatomy and variations of the human extensor tendons of the fingers and their intertendinous connections. Ninetyfive upper limbs of adult cadavers were dissected. The variations in the extensor tendons of the fingers, both proximal and distal to the extensor retinaculum, and their mode of insertion were ...
G A, Abdel-Hamid   +2 more
openaire   +3 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Canalis sinuosus: a rare anatomical variation

open access: yes, 2015
The infraorbital canal issues a small branch on its lateral face close to its midpoint to allow passage of the anterior superior alveolar nerve. This small canal, sometimes called the canalis sinuosus, runs forward and downward to the inferior wall of ...
Caria, PHF   +5 more
core   +1 more source

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