Results 261 to 270 of about 1,826,835 (356)

Mirizzi Syndrome With a Hepatic Duct Confluence Fistula and Stone Migration Into the Left Hepatic Duct: A Case Report. [PDF]

Cureus
Siribaddana H, Kandpal H, Grimpen F, Goh I, Chandrasegaram MD.   +4 more
europepmc   +1 more source

Functional Anatomy of Acrosin Inhibitors [PDF]

, 1975
Fink, Edwin, Fritz, Hans, Klauser, R., Kupfer, S., Tschesche, Harald   +4 more
core  

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Reflections on the value of near-peer teaching in anatomy education. [PDF]

Can Med Educ J
Coello ADG.
europepmc   +1 more source

High photosynthesis rates in Brassiceae species are mediated by leaf anatomy enabling high biochemical capacity, rapid CO₂ diffusion and efficient light use [PDF]

Moges Retta, Leen Van Doorselaer, Steven M. Driever, Xinyou Yin, N.C.A. de Ruijter, Pieter Verboven, Bart Nicolaı̈, P.C. Struik   +7 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Erratum: The clinical value of spectral computed tomography reconstruction technology for the anatomy of the superior mesenteric artery in laparoscopic radical right hemicolectomy for colon cancer: a cross-sectional study. [PDF]

J Gastrointest Oncol
Editorial Office.
europepmc   +1 more source

Gamifying anatomy outreach: An underexplored opportunity [PDF]

Mikaela L. Stiver, Aamna Naveed, John K. Chilton, Siobhan M. Moyes   +3 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Reimagining Anatomy Education: The Potential of Virtual Learning. [PDF]

Cureus
Linkwinstar J, Ashraf I, Noor Chaudhry K, Jery G, Saleem N, Akhlaq H.   +5 more
europepmc   +1 more source